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91社区 Researchers Show Immune System Linked to Leprosy Susceptibility
Published: 17 December 2009
(Modern Medicine) Researchers at 91社区 performed a genome-wide association study linking innate immunity to leprosy infections. An attractive aspect of the study "is the apparently narrow focus of the genetic control, which highlights early antigen sensing and signaling in the pathogenesis of both leprosy and Crohn's disease," writes Erwin Schurr, Ph.D., and Philippe Gros, Ph.D in an accompanying editorial published Dec. 16 in the New England Journal of Medicine. "It is tempting to speculate that these common genetic signatures support, albeit indirectly, the proposal that a proportion of Crohn's disease cases may have a mycobacterial cause."