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Improving research with more effective antibodies

Scientists demonstrate flaws in protein detection tools, and outline a solution

A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly.

Antibodies are used in laboratories and clinics to study proteins, which are the biomolecules that translate information from an organism鈥檚 genes into the structure, function, and regulation of its tissues and organs. Genetic mutations can cause protein imbalances or malfunctions, leading to human disease.

Classified as: ALS, Peter McPherson, antibodies, proteins, genetics, reproducibility, amyotrophic lateral sclerosis, genes
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Published on: 15 Oct 2019

The link between obesity, the brain, and genetics

When it comes to weight gain, the problem may be mostly in our heads, and our genes

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.

Classified as: alain dagher, Uku Vainik, obesity, brain volume, MRI, human connectome project, PNAS
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Published on: 28 Aug 2018

Unique brain 鈥渇ingerprint鈥� can predict drug effectiveness

Technique can be used to better categorize patients with neurological disease, according to their therapeutic needs

Personalized medicine 鈥� delivering therapies specially tailored to a patient鈥檚 unique physiology 鈥� has been a goal of researchers and doctors for a long time. New research provides a way of delivering personalized treatments to patients with neurological disease.

Classified as: Ludmer Centre, neuroinformatics, The Neuro, Neuro, MNI, Yasser Iturria Medina, Dr Yasser Iturria-Medina, Yasser Iturria-Medina
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Published on: 10 Jul 2018

Early HIV treatment key to avoiding brain atrophy

New study underlines importance of early screening and antiretroviral therapy

While the human immunodeficiency virus (HIV) has largely dropped from news headlines since the 1990s, at the end of 2016 there were 36.7 million people living with the infection, and of those only 53 per cent had access to treatment. A new study underscores the neurological consequences of exposure to HIV without antiretroviral therapy.

Classified as: HIV, Louis Collins, Ryan Sanford, brain atrophy, MRI, cART
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Published on: 3 May 2018

June is Stroke Month

The Neuro is an important centre for stroke care in Montreal

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The Montreal Neurological Institute (The Neuro) is marking Stroke Month in June to increase public awareness about the dangers of this serious condition, and the importance of early intervention. A Canadian suffers a stroke every ten minutes. Each year, about 14,000 Canadians die of stroke, making stroke the third-leading cause of death in this country.

Classified as: stroke, stroke month, Donatella Tampieri, Jeanne Teitelbaum, Maria Del Pilar Cortes Nino
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Published on: 1 Jun 2017

Turning skin cells into brain cells

Microglia, critical to Alzheimer鈥檚 research, can now be produced artificially

The quest for better understanding of Alzheimer鈥檚 disease (AD) has a powerful new tool at its disposal 鈥� the ability to artificially generate brain cells that have been shown to play an important role in the disease function.

Classified as: stem cells, iPSC, Alzheimer's disease, MS, Jack Antel, Luke Healy, microglia
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Published on: 16 May 2017

Improving memory with magnets

Discovery expands our understanding of how we remember sound

The ability to remember sounds, and manipulate them in our minds, is incredibly important to our daily lives 鈥� without it we would not be able to understand a sentence, or do simple arithmetic. New research is shedding light on how sound memory works in the brain, and is even demonstrating a means to improve it.

Classified as: Montreal Neurological Institute, Neuroimaging and Neuroinformatics, Neurocognition, Sylvain Baillet, Robert Zatorre, Dr. Robert Zatorre
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Published on: 27 Mar 2017

Molecule shown to repair damaged axons

Discovery could be key to treating brain and spinal cord injury

A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke.

Classified as: Neuro, MNI, stroke, Neurology, spinal cord injury, axon repair, 14-3-3, Fusicoccin-A, Alyson Fournier
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Published on: 8 Mar 2017

Bell Let鈥檚 Talk supports mental health with The Neuro

Project will enhance mental health access for multicultural communities

On Jan. 18, 2017, Bell Let鈥檚 Talk announced a donation of $250,000 to 91社区鈥檚 Montreal Neurological Institute and Hospital 鈥� known as The Neuro 鈥� to fund the development of online mental health resources focused on the needs of multicultural communities.

Classified as: Bell Let's Talk, Bell, mental health, Multicultural Mental Health Resource Centre, Guy Rouleau
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Published on: 18 Jan 2017

Breakthrough in MS treatment

Drug shown to reduce new attacks/symptom progression in some patients

In separate clinical trials, a drug called ocrelizumab has been shown to reduce new attacks in patients with relapsing remitting multiple sclerosis (MS), and new symptom progression in primary progressive MS.

Classified as: MS, ocrelizumab, Amit Bar-Or, Douglas Arnold, Multiple Sclerosis
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Published on: 22 Dec 2016

Major ALS Research Funding Announced

MNI scientists will study stem cells, genetic mutations to develop new treatments

Researchers at the Montreal Neurological Institute of 91社区 who are playing key roles in uncovering the mechanisms underlying ALS will share in $3.9 million in research funding, part of $4.5 million announced on Nov. 23 by the ALS Society of Canada in partnership with Brain Canada.

Classified as: ALS, Brain Canada, C9ORF72, Canada Brain Research Fund, ALS Society of Canada, Gary Armstrong, Patrick Dion, Stefano Stifani, Peter McPherson, Guy Rouleau
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Published on: 23 Nov 2016

Canada AM

Dr. Joe sits down with Bev Thomson on Canada AM and chats about his new book, "Monkeys, Myths, and Molecules."

Click to see the full interview.

Classified as: Joe Schwarcz, book review, Office for Science and Society, CTV, Canada AM
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Published on: 12 May 2015

Covering conflict in the world鈥檚 deadliest places

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Published on: 21 Mar 2010
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