BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250331T224311EDT-5839rAGj2R@132.216.98.100 DTSTAMP:20250401T024311Z DESCRIPTION:La conf茅rence Olszewski du Neuro\, cr茅茅e en 1986\, rend hommage au Dr Jerzy Olszewski (1913鈥�1964)\, un neuroanatomiste et neuropathologis te pionnier. Invit茅 au Neuro par le Dr Wilder Penfield en 1948\, Olszewski a collabor茅 脿 l鈥檕uvrage fondamental Cytoarchitecture of the Human Brain S tem\, contribuant 脿 l鈥檃vancement de la compr茅hension des structures du tro nc c茅r茅bral et 茅tablissant son h茅ritage dans le domaine des neurosciences. \n\n\nPour assister en personne\,聽inscrivez-vous ici\n\nPour regarder via Vimeo\,聽cliquez ici\n\n\nXiaowei Zhuang聽\n\nHoward Hughes Medical Institut e\, Harvard University\n\nAbstract: Cell and tissue functions arise from t he coordinated activities of thousands of different genes. Understanding t hese functions requires imaging at the genome scale\, which advances knowl edge in many areas of biology\, from the regulation of gene expression in cells to the development of cell fate and the organization of cell types i n complex tissues. A single-cell genome-scale imaging method\, multiplexed error-robust fluorescence in situ hybridization (MERFISH)\, was developed to enable spatially resolved single-cell transcriptomics\, epigenomics\, 3D-genomics\, and functional genomics. This method allows for single-cell gene-expression profiling in intact tissues\, facilitating the identificat ion\, spatial mapping\, and functional investigation of distinct cell type s within those tissues. Using this approach\, molecularly defined\, spatia lly resolved\, and functionally annotated cell atlases of the brain have b een created. This lecture will describe the MERFISH technology and its app lications\, with a particular focus on mapping the molecular\, spatial\, a nd functional organizations of distinct cell types in the brain.\n DTSTART:20250327T200000Z DTEND:20250327T210000Z LOCATION:de Grandpre Communications Centre\, Montreal Neurological Institut e\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University SUMMARY:Olszewski Lecture: Spatially Resolved Single-Cell Genomics & Cell A tlas of the Brain URL:/neuro/fr/channels/event/olszewski-lecture-spatial ly-resolved-single-cell-genomics-cell-atlas-brain-361354 END:VEVENT END:VCALENDAR