2025 Neuro Epilepsy Day and Pierre Gloor Lecture
The Neuro Epilepsy Day is a half-day event. The day will focus on neurodegeration and tauopathy in epilepsy, and its implications for cognition and disease progression.
Watch online . No registration required.
The Pierre Gloor lecture honours the life and legacy of Pierre Gloor (1923-2003) who joined 91社区's Montreal Neurological Institute in 1952 as a fellow in electroencephalography and neurophysiology. He studied with Wilder Penfield and Herbert Jasper, eventually receiving his Ph.D. from 91社区 in 1957. Pierre Gloor worked closely with the clinical and research teams at the Montreal Neurological Institute in the treatment of epilepsy. His work in understanding and treating this disorder earned him a worldwide reputation.
Thursday, May 29, 2025
| 11:00 |
Welcome and Introduction Boris Bernhardt, PhD |
| 11:15 |
Trainee Presentations Host: Alex Barnett, PhD |
| 12:15 |
Lunch and Poster Session |
| 13:45 |
Pierre Gloor Lectures Welcome and Speaker Introduction:听Raluca Pana, MD Evidence for Neurodegenerative Pathology in Epilepsy Lecture 2 |
| 15:45 |
Closing Remarks Boris Bernhardt and Raluca Pana |
Speakers
Maria Thom
Bio
I am an academic neuropathologist working at the UCL Queen Square Institute of Neurology, London and have a research interest in epilepsy in addition to providing a clinical diagnostic service. I have set up an epilepsy brain and tissue bank at UCL supported by the Epilepsy Society, which facilitates the archiving and use of human tissue samples for varied research projects across several centres. My personal research in recent years has focused on neurodegenerative cellular mechanisms in epilepsy and correlations with MRI, supported by the Wellcome Trust. Other studies focus on the Neuropathology findings in sudden and unexpected death in epilepsy and pathogenesis of focal surgical pathologies including hippocampal sclerosis and focal cortical dysplasia. I contribute regularly to Euro CNS and ILAE neuropathology teaching courses on epilepsy pathology over the last decade and have been a member of the ILAE diagnostic commission task forces . I am an author of several book chapters in this field, including the 2024 10th edition of Greenfields Neuropathology and I am executive editor for the journal Neuropathology and Applied Neurobiology for epilepsy.
Abstract
Cognitive decline in older adults with epilepsy represents a significant co-morbidity and people with epilepsy are also more at risk for developing dementia. In addition to hippocampal damage, progressive cortical atrophy is a prominent finding on MRI, especially in drug-resistant focal epilepsy and the ENIGMA-epilepsy consortium demonstrated common patterns of cortical atrophy in focal epilepsies. However, the pattern of atrophy in epilepsy differs from that seen in Alzheimer鈥檚 disease (AD) or chronic traumatic encephalopathy (CTE) and the precise neuropathology correlates are uncertain.
In tissue samples from patients operated for drug refractory epilepsy as well as post-mortem series we have been exploring the evidence and prevalence of neurodegenerative pathology including tauopathy, as AD and CTE, small vessel disease and cortical atrophy. This has been correlated with neuroimaging parameters and neuropsychology profiles in an aim to predict neuropathology biomarkers that could be relevant to any memory decline in epilepsy.
Matthias Koepp
Bio
TBD
Abstract
TBD
Location
The Montreal Neurological Institute and Hospital is at 3801 University Street, north of Pine Avenue West, on the 91社区 campus opposite the former Royal Victoria Hospital.
Montreal is served by highway Routes 10, 15, 20 and 40, and by Greyhound Bus, Via Rail and the P-E-Trudeau airport. In the city, bus and metro service is provided by the Soci茅t茅 de transport de Montr茅al (STM).
Wheelchair access
A wheelchair accessible entrance is on University Street north of the main entrance. Another wheelchair accessible entrance is in the loading area behind the building: to enter the loading area, turn into the driveway south of the main entrance. Please note, there is no parking in the loading area.
Parking
Parking near the MNI is sometimes difficult. There are parking meters on University Street and a parking lot north of the main entrance. To enter the lot, turn right into the driveway toward Molson Stadium.
Information about parking fees
Taxi Stand
There is a taxi stand on University Street across from the main entrance. You may call a cab from the free taxi phone in the main lobby near the Security Desk.
Access by Public Transportation听
Bus
There are four bus stops within walking distance:
- Bus 144 stops at Pine Avenue and University Street
- Bus 356 stops at Sherbrooke Street and University Street (Nightbus)
- Bus 107 stops at Pine Avenue and Docteur Penfield
- Bus 24 stops at Sherbrooke Street and University Street
Metro
Take the Metro Green Line to the 91社区 station. Walk north on University Street and cross Pine Avenue. The main entrance is on the right, past the flags.
Jeanne Timmins Amphitheatre
- Enter the main lobby, turn left, and go down the hallway to the end.
- Turn right and go down the second hallway until you see another hallway on the left.
- This hallway leads to the Jeanne Timmins Foyer.
- On your听right听are the Jeanne Timmins Amphitheatre entrance doors.
Call for Posters听
Sharing Science and Knowledge
Trainees at the undergraduate, graduate, and postdoctoral level are invited to present their work as posters. Abstracts will also be considered for an oral presentation.听
The scientific presentations are intended to ignite discussion, collaboration, and connection among the Montreal epilepsy community. We encourage you to share your most current project in any stage of development, research questions, and pilot projects.听
The deadline for submission is April 25, 2025.
Scientific Committee
Boris Bernhardt
Raluca Pana
Alexander Barnett
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