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Program Requirements
Revision, August 2011. Start of revision. Students should register at the Major level in U1 and, if accepted, may enter the Honours program at the beginning of U2. To enter the program, the student must obtain a CGPA of at least 3.20 at the end of U1. For promotion to the U3 year of the Honours program, or for entry into the program at this level, the student must have a CGPA of at least 3.20 at the end of their U2 year. It is expected that at the beginning of the third year, the students who wish to continue in the Honours program will be those who feel that they are seriously interested in a career in Cell Biology. The Honours degree will be recommended after successful completion of the program with a CGPA of at least 3.20.Required Courses (52 credits)
Note: ANAT 261 must be taken in U1.
* Students who have taken the equivalent of CHEM 212, CHEM 222, and/or MATH 203 in CEGEP (as defined at ) are exempt and must replace these credits with elective course credits to satisfy the total credit requirement for their degree.
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ANAT 212 Molecular Mechanisms of Cell Function (3 credits)
Overview
Anatomy & Cell Biology : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.
Terms: Winter 2012
Instructors: Pause, Arnim; Bouchard, Maxime; Young, Jason (Winter)
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ANAT 214 Systemic Human Anatomy (3 credits)
Overview
Anatomy & Cell Biology : Introduction to the gross anatomy of the various organ systems of head, neck and trunk regions of the human body. Practical tutorials include studies of prepared specimens, use of the anatomical museum and audio-visual materials. This course is limited in size. Selection of students (other than those requiring the course as part of their program) will be made after the first lecture. (Admission is guaranteed for all students enrolled in programs in the Department of Anatomy and Cell Biology for which ANAT 214 is a required course.)
Terms: Fall 2011
Instructors: Hermo, Louis (Fall)
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ANAT 261 Introduction to Dynamic Histology (4 credits)
Overview
Anatomy & Cell Biology : An introduction to light and electron microscopic anatomy in which cell and tissue dynamics will be explored in the principal tissues and organs of the body.
Terms: Fall 2011
Instructors: Mandato, Craig A.; Morales, Carlos R (Fall)
Fall
3 hours lectures, 2 hours laboratory
Must be taken in U1 by students in Anatomy and Cell Biology programs
Prerequisite: BIOL 112 or CEGEP equivalent
Restriction: Open to students in biological sciences and others by special permission
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ANAT 262 Introductory Molecular and Cell Biology (3 credits)
Overview
Anatomy & Cell Biology : The architectural, functional and temporal continuity of organelles and the cytoskeleton of mammalian cells is introduced as well as their functional integration in the phenomena of exocytosis, endocytosis, protein trafficking and cell motility and adhesion.
Terms: Winter 2012
Instructors: Presley, John; Stochaj, Ursula; Bedford, Fiona Kay (Winter)
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ANAT 432 Honours Research Project (9 credits)
Overview
Anatomy & Cell Biology : Supervised honours research project in biological sciences.
Terms: Summer 2012, Fall 2011, Winter 2012
Instructors: Bedford, Fiona Kay (Summer) Bedford, Fiona Kay (Fall) Bedford, Fiona Kay (Winter)
Prerequisite: BIOL 301
Restriction: For students in the Honours program.
Course opened to all Anatomy & Cell Biology students and other BSc students by special permission only.
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BIOL 200 Molecular Biology (3 credits)
Overview
Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.
Terms: Fall 2011
Instructors: Bureau, Thomas E; Roy, Richard D W; Fagotto, Francesco; Zetka, Monique (Fall)
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BIOL 202 Basic Genetics (3 credits)
Overview
Biology (Sci) : Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.
Terms: Winter 2012, Summer 2012
Instructors: Western, Tamara; Chevrette, Mario; Hendry, Andrew (Winter) Dankort, David; Hipfner, David (Summer)
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BIOL 301 Cell and Molecular Laboratory (4 credits)
Overview
Biology (Sci) : An introduction to laboratory techniques with a focus on methods used to investigate fundamental questions in modern cell and molecular biology. Techniques including gene cloning, DNA and protein isolation and manipulation are covered, along with functional analysis of genes and proteins, basic bioinformatics, and computer-based experimental design and data analysis.
Terms: Fall 2011, Winter 2012
Instructors: Moon, Nam Sung; Dent, Joseph Alan; Zheng, Huanquan (Fall) Moon, Nam Sung; Harrison, Paul; Zheng, Huanquan (Winter)
Fall or Winter
1 hour lecture and one 6-hour laboratory
Prerequisites: PHYS 102 or PHYS 142, BIOL 200, BIOL 201 or ANAT/BIOC 212, and BIOL 202. BIOL 206 recommended.
Restrictions: Not open to students who have taken or are taking BIOC 300. Requires departmental approval.
For approval email anne-marie.sdicu [at] mcgill.ca. Specify your ID number as well as the term and lab day.
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CHEM 212 Introductory Organic Chemistry 1 (4 credits) *
Overview
Chemistry : A survey of reactions of aliphatic and aromatic compounds including modern concepts of bonding, mechanisms, conformational analysis, and stereochemistry.
Terms: Fall 2011, Winter 2012, Summer 2012
Instructors: Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc; Tsantrizos, Youla S (Fall) Harpp, David Noble; Schirrmacher, Ralf; Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc (Winter) Fenster, Ariel; Daoust, Michel (Summer)
Fall, Winter, Summer
Prerequisite: CHEM 110 or equivalent.
Corequisite: CHEM 120 or equivalent.
Restriction: Not open to students who are taking or have taken CHEM 211 or equivalent
Each lab section is limited enrolment
Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page ().
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CHEM 222 Introductory Organic Chemistry 2 (4 credits) *
Overview
Chemistry : Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.
Terms: Fall 2011, Winter 2012, Summer 2012
Instructors: Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc; Harpp, David Noble; Perepichka, Dmytro (Fall) Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc; Auclair, Karine (Winter) Daoust, Michel; Schwarcz, Joseph A (Summer)
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MIMM 314 Immunology (3 credits)
Overview
Microbiology and Immun (Sci) : An introduction to the immune system, antigens, antibodies and lymphocytes. The course will cover the cellular and molecular basis of lymphocyte development and mechanisms of lymphocyte activation in immune responses.
Terms: Winter 2012
Instructors: Piccirillo, Ciriaco; Alizadehfar, Reza; Fournier, Sylvie (Winter)
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PHGY 209 Mammalian Physiology 1 (3 credits)
Overview
Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.
Terms: Fall 2011
Instructors: Wechsler, Ann; Gold, Phil; Ragsdale, David S (Fall)
Fall
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
Restriction: Not open to students who have taken PHGY 211 or PHGY 201 or students who are taking and who have taken NSCI 200.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
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PHGY 210 Mammalian Physiology 2 (3 credits)
Overview
Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.
Terms: Winter 2012
Instructors: White, John H; Wechsler, Ann; Takano, Tomoko (Winter)
Winter
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisite: BIOL 200, BIOL 201, BIOC 212, CHEM 212 or equivalent.
Restriction: Not open to students who have taken PHGY 202.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
Although PHGY 210 may be taken without the prior passing of PHGY 209, students should note that they may have some initial difficulties because of lack of familiarity with some basic concepts introduced in PHGY 209
One of the following statistics courses:
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BIOL 373 Biometry (3 credits)
Overview
Biology (Sci) : Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages.
Terms: Fall 2011
Instructors: Leung, Brian (Fall)
Fall
2 hours lecture and 2 hours laboratory
Prerequisite: MATH 112 or equivalent
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
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MATH 203 Principles of Statistics 1 (3 credits) *
Overview
Mathematics & Statistics (Sci) : Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions).
Terms: Fall 2011, Winter 2012, Summer 2012
Instructors: Khalili Mahmoudabadi, Abbas; Genest, Christian (Fall) Wolfson, David B (Winter) Hundemer, Axel W (Summer)
No calculus prerequisites
Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult for information regarding transfer credits for this course.
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PSYC 204 Introduction to Psychological Statistics (3 credits)
Overview
Psychology : The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance.
Terms: Fall 2011, Winter 2012, Summer 2012
Instructors: Amsel, Rhonda N (Fall) Ostry, David J (Winter) Zangenehpour, Shahin (Summer)
Fall and Winter
Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300
This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
Complementary Courses (21 credits)
Complementary courses are selected as follows with a minimum of 6 credits at the 400 level or higher:
18 credits selected from:
* Note: Students may take either ANAT 321 OR ANAT 323.
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ANAT 321 Circuitry of the Human Brain (3 credits) *
Overview
Anatomy & Cell Biology : This course explores the functional organization of the human brain and spinal cord. The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations.
Terms: Fall 2011
Instructors: Brawer, James; David, Samuel (Fall)
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ANAT 322 Neuroendocrinology (3 credits)
Overview
Anatomy & Cell Biology : A lecture course describing brain-endocrine relationships. Emphasis on modern experimental evidence and conceptual developments within the field.
Terms: Winter 2012
Instructors: Walker, Claire; Stroh, Thomas; Goodyer, Cynthia (Winter)
Winter
3 hours lecture
Prerequisite: ANAT 261.
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ANAT 323 Neuroanatomy (3 credits) *
Overview
Anatomy & Cell Biology : This course will focus on the structural and functional relationships of the central nervous system. The human neuroanatomy will be introduced via pathological cases and will be illustrated by use of new medical imaging techniques.
Terms: Fall 2011
Instructors: Noel, Geoffroy (Fall)
Prerequisites for Physical & Occupational Therapy students: ANAT 315 and ANAT 316.
Prerequisite for Honours Anatomy & Cell Biology students: ANAT 214.
Restrictions: Restricted to Honours Anatomy & Cell Biology students and Physical & Occupational Therapy students. Not open to students taking or having taken ANAT 321.
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ANAT 365 Cellular Trafficking (3 credits)
Overview
Anatomy & Cell Biology : An intensive study of the processes of protein secretion and cell membrane biogenesis. Emphasis on morphological aspects of the above processes, and on the major techniques which have provided experimental evidence, namely, subcellular fractionation, cytochemistry and quantitative electron microscope radioautography.
Terms: Fall 2011
Instructors: Bedford, Fiona Kay; McBride, Heidi; McPherson, Peter Scott (Fall)
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ANAT 381 Basis of Embryology (3 credits)
Overview
Anatomy & Cell Biology : The basic processes of reproduction and embryonic development, such as molecular signaling; cell-cell interaction; differentiation; cell fate determination; genetic and epigenetic control of embryonic development.
Terms: Fall 2011
Instructors: Nagano, Makoto; Chian, Ri-Cheng; Ao, Asangla (Fall)
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ANAT 416 Development, Disease and Regeneration (3 credits)
Overview
Anatomy & Cell Biology : Importance of developmental biology for disease and regeneration. Topics: advanced developmental biology principles; molecular basis for stem cells and their potential applications; organogenesis and its applications to various diseases.
Terms: Winter 2012
Instructors: Mandato, Craig A.; Kania, Artur; Charron, Frederic (Winter)
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ANAT 458 Membranes and Cellular Signaling (3 credits)
Overview
Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2012
Instructors: Silvius, John R; Lamarche, Nathalie; Bedford, Fiona Kay (Winter)
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ANAT 541 Cell and Molecular Biology of Aging (3 credits)
Overview
Anatomy & Cell Biology : Complex aging process, including theories and mechanisms of aging, animal model systems used to study aging, age-dependent diseases, for example, Alzheimer's, osteoporosis, and cancer, and age-related diseases, for example, Werner's syndrome and dyskeratosis congenita.
Terms: Winter 2012
Instructors: Lehoux, Stephanie; Henderson, Janet; LeBlanc, Andrea (Winter)
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ANAT 565 Diseases-Membrane Trafficking (3 credits)
Overview
Anatomy & Cell Biology : This course will examine how research into diseases has played a key role in unraveling the intricate molecular mechanisms controlling membrane trafficking in mammalian cells. Membrane trafficking disorders fall into two groups those arising from a) membrane-associated or b) cytoskeletal defect. Topics include a) mechanisms of endosomal maturation, lysosomal storage disorders and rab protein-mediated vesicular trafficking and b) rho GTPase and cytoskeletal binding protein mediated trafficking associated with neurological diseases and cancer.
Terms: Winter 2012
Instructors: Bedford, Fiona Kay; McBride, Heidi; Lamarche, Nathalie (Winter)
Prerequisite: ANAT 365
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NEUR 310 Cellular Neurobiology (3 credits)
Overview
Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.
Terms: Winter 2012
Instructors: Cloutier, Jean-Francois; Ragsdale, David S; Kennedy, Timothy E (Winter)
3 credits of biologically oriented courses (BOC) selected from:
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ANAT 322 Neuroendocrinology (3 credits)
Overview
Anatomy & Cell Biology : A lecture course describing brain-endocrine relationships. Emphasis on modern experimental evidence and conceptual developments within the field.
Terms: Winter 2012
Instructors: Walker, Claire; Stroh, Thomas; Goodyer, Cynthia (Winter)
Winter
3 hours lecture
Prerequisite: ANAT 261.
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ANAT 365 Cellular Trafficking (3 credits)
Overview
Anatomy & Cell Biology : An intensive study of the processes of protein secretion and cell membrane biogenesis. Emphasis on morphological aspects of the above processes, and on the major techniques which have provided experimental evidence, namely, subcellular fractionation, cytochemistry and quantitative electron microscope radioautography.
Terms: Fall 2011
Instructors: Bedford, Fiona Kay; McBride, Heidi; McPherson, Peter Scott (Fall)
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ANAT 381 Basis of Embryology (3 credits)
Overview
Anatomy & Cell Biology : The basic processes of reproduction and embryonic development, such as molecular signaling; cell-cell interaction; differentiation; cell fate determination; genetic and epigenetic control of embryonic development.
Terms: Fall 2011
Instructors: Nagano, Makoto; Chian, Ri-Cheng; Ao, Asangla (Fall)
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ANAT 416 Development, Disease and Regeneration (3 credits)
Overview
Anatomy & Cell Biology : Importance of developmental biology for disease and regeneration. Topics: advanced developmental biology principles; molecular basis for stem cells and their potential applications; organogenesis and its applications to various diseases.
Terms: Winter 2012
Instructors: Mandato, Craig A.; Kania, Artur; Charron, Frederic (Winter)
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ANAT 432 Honours Research Project (9 credits)
Overview
Anatomy & Cell Biology : Supervised honours research project in biological sciences.
Terms: Summer 2012, Fall 2011, Winter 2012
Instructors: Bedford, Fiona Kay (Summer) Bedford, Fiona Kay (Fall) Bedford, Fiona Kay (Winter)
Prerequisite: BIOL 301
Restriction: For students in the Honours program.
Course opened to all Anatomy & Cell Biology students and other BSc students by special permission only.
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ANAT 458 Membranes and Cellular Signaling (3 credits)
Overview
Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2012
Instructors: Silvius, John R; Lamarche, Nathalie; Bedford, Fiona Kay (Winter)
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ANAT 541 Cell and Molecular Biology of Aging (3 credits)
Overview
Anatomy & Cell Biology : Complex aging process, including theories and mechanisms of aging, animal model systems used to study aging, age-dependent diseases, for example, Alzheimer's, osteoporosis, and cancer, and age-related diseases, for example, Werner's syndrome and dyskeratosis congenita.
Terms: Winter 2012
Instructors: Lehoux, Stephanie; Henderson, Janet; LeBlanc, Andrea (Winter)
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ANAT 565 Diseases-Membrane Trafficking (3 credits)
Overview
Anatomy & Cell Biology : This course will examine how research into diseases has played a key role in unraveling the intricate molecular mechanisms controlling membrane trafficking in mammalian cells. Membrane trafficking disorders fall into two groups those arising from a) membrane-associated or b) cytoskeletal defect. Topics include a) mechanisms of endosomal maturation, lysosomal storage disorders and rab protein-mediated vesicular trafficking and b) rho GTPase and cytoskeletal binding protein mediated trafficking associated with neurological diseases and cancer.
Terms: Winter 2012
Instructors: Bedford, Fiona Kay; McBride, Heidi; Lamarche, Nathalie (Winter)
Prerequisite: ANAT 365
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BIOC 311 Metabolic Biochemistry (3 credits)
Overview
Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.
Terms: Fall 2011
Instructors: St-Pierre, Julie; Dostie, Josee; Nagar, Bhushan (Fall)
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BIOC 312 Biochemistry of Macromolecules (3 credits)
Overview
Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).
Terms: Winter 2012
Instructors: Nepveu, Alain; Sonenberg, Nahum; Shore, Gordon C (Winter)
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BIOC 450 Protein Structure and Function (3 credits)
Overview
Biochemistry : Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.
Terms: Fall 2011
Instructors: Nagar, Bhushan; Schmeing, Thomas Martin; Gotte, Matthias (Fall)
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BIOC 458 Membranes and Cellular Signaling (3 credits)
Overview
Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2012
Instructors: Silvius, John R; Lamarche, Nathalie; Bedford, Fiona Kay (Winter)
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BIOC 503 Immunochemistry (3 credits)
Overview
Biochemistry : This course, presented in lecture format, emphasizes the molecular, genetic and structure function events that occur in the humoral immune response. Interleukins and other mediators of inflammation, a field in which rapid changes are occurring, are discussed. The clinical significance of fundamental biochemical findings is described.
Terms: Winter 2012
Instructors: Shuster, Joseph (Winter)
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BIOL 300 Molecular Biology of the Gene (3 credits)
Overview
Biology (Sci) : A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.
Terms: Fall 2011
Instructors: Schöck, Frieder; Nilson, Laura; Rocheleau, Christian (Fall)
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BIOL 301 Cell and Molecular Laboratory (4 credits)
Overview
Biology (Sci) : An introduction to laboratory techniques with a focus on methods used to investigate fundamental questions in modern cell and molecular biology. Techniques including gene cloning, DNA and protein isolation and manipulation are covered, along with functional analysis of genes and proteins, basic bioinformatics, and computer-based experimental design and data analysis.
Terms: Fall 2011, Winter 2012
Instructors: Moon, Nam Sung; Dent, Joseph Alan; Zheng, Huanquan (Fall) Moon, Nam Sung; Harrison, Paul; Zheng, Huanquan (Winter)
Fall or Winter
1 hour lecture and one 6-hour laboratory
Prerequisites: PHYS 102 or PHYS 142, BIOL 200, BIOL 201 or ANAT/BIOC 212, and BIOL 202. BIOL 206 recommended.
Restrictions: Not open to students who have taken or are taking BIOC 300. Requires departmental approval.
For approval email anne-marie.sdicu [at] mcgill.ca. Specify your ID number as well as the term and lab day.
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BIOL 303 Developmental Biology (3 credits)
Overview
Biology (Sci) : A consideration of the fundamental processes and principles operating during embryogenesis. Experimental analyses at the molecular, cellular, and organismal levels will be presented and discussed to provide an overall appreciation of developmental phenomena.
Terms: Winter 2012
Instructors: Nilson, Laura; Rao, Yong; Dufort, Daniel (Winter)
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BIOL 306 Neural Basis of Behaviour (3 credits)
Overview
Biology (Sci) : Neural mechanisms of animal behaviour; neuroethology; cellular neurophysiology, integrative networks within nervous systems; neural control of movement; processing of sensory information.
Terms: Fall 2011
Instructors: Pollack, Gerald; Dent, Joseph Alan; Krahe, Rudiger (Fall)
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BIOL 313 Eukaryotic Cell Biology (3 credits)
Overview
Biology (Sci) : Cell biology of eukaryotes focusing on the assembly and function of cellular structures, the regulation of transcription; the dynamics of the cytoskeleton and its motors; mechanics of cell division; cell cycle and checkpoints; nuclear dynamics; chromosome structure and behaviour and experimental techniques.
Terms: Winter 2012
Instructors: Zetka, Monique; Fagotto, Francesco (Winter)
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BIOL 314 Molecular Biology of Oncogenes (3 credits)
Overview
Biology (Sci) : The genes that cause cancer are altered versions of genes present in normal cells. The origins of these oncogenes, their genetic structure, regulation, and the biochemical properties of the oncogene-encoded proteins will be analyzed in an attempt to understand the origins of human and animal cancers.
Terms: Fall 2011
Instructors: Majewska, Loydie; Jabado, Nada; Duchaine, Thomas (Fall)
- BIOL 370 Human Genetics Applied (3 credits)
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BIOL 514 Neurobiology Learning and Memory (3 credits)
Overview
Biology (Sci) : Properties of nerve cells that are responsible for learning and memory. Recent advances in the understanding of neurophysiological, biochemical and structural processes relevant to neural plasticity. Emphasis on a few selected model systems involving both vertebrate and invertebrate animals.
Terms: Winter 2012
Instructors: Nader, Karim (Winter)
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BIOL 518 Advanced Topics in Cell Biology (3 credits)
Overview
Biology (Sci) : Concepts and mechanisms in advanced cell biology, based on genetic, cell biological, biophysical, and computational studies. Emphasis is placed on processes that are evolutionarily conserved, with examples from model organisms and cell-free (in vitro) approaches.
Terms: Winter 2012
Instructors: Brouhard, Gary; Vogel, Jacalyn (Winter)
Winter
3 hours seminar
Prerequisite: BIOL 313 or permission
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BIOL 520 Gene Activity in Development (3 credits)
Overview
Biology (Sci) : An analysis of the role and regulation of gene expression in several models of eukaryotic development. The emphasis will be on critical evaluation of recent literature concerned with molecular or genetic approaches to the problems of cellular differentiation and determination. Recent research reports will be discussed in conferences and analyzed in written critiques.
Terms: Winter 2012
Instructors: Roy, Richard D W (Winter)
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BIOL 524 Topics in Molecular Biology (3 credits)
Overview
Biology (Sci) : Molecular genetics and molecular, cellular and developmental biology, including signal transduction, cell differentiation and function, genetic diseases in eukaryotes.
Terms: Fall 2011
Instructors: Clarke, Hugh; Dankort, David (Fall)
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BIOL 532 Developmental Neurobiology Seminar (3 credits)
Overview
Biology (Sci) : Discussions of all aspects of nervous system development including pattern formation, cell lineage, pathfinding and targeting by growing axons, and neural regeneration. The basis for these discussions will be recent research papers and other assigned readings.
Terms: Winter 2012
Instructors: Van Meyel, Donald; Kania, Artur; Fournier, Alyson Elise (Winter)
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BIOL 544 Genetic Basis of Life Span (3 credits)
Overview
Biology (Sci) : The course will consider how gene action is determining the duration of life in various organisms focusing on the strengths and limitations of the genetic approach. The course will focus particularly on model organisms such as yeast, Caenorhabditis, Drosophila and mouse, as well as on the characterization of long-lived people.
Terms: Fall 2011
Instructors: Hekimi, Siegfried (Fall)
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BIOL 551 Molecular Biology: Cell Cycle (3 credits)
Overview
Biology (Sci) : Cytological studies, biochemical and genetical information are integrated to explain molecular form and function in the eukaryotic cell. The mitotic cell cycle and its coordination with cell growth and division; maintenance of cellular architecture, protein targeting, self-assembly of macromolecular complexes, organelle biogenesis, and DNA replication and segregation are examined.
Terms: Winter 2012
Instructors: Vogel, Jacalyn (Winter)
- BIOL 575 Human Biochemical Genetics (3 credits)
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BIOL 588 Advances in Molecular/Cellular Neurobiology (3 credits)
Overview
Biology (Sci) : Discussion of fundamental molecular mechanisms underlying the general features of cellular neurobiology. An advanced course based on lectures and on a critical review of primary research papers.
Terms: This course is not scheduled for the 2011-2012 academic year.
Instructors: There are no professors associated with this course for the 2011-2012 academic year.
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BIOT 505 Selected Topics in Biotechnology (3 credits)
Overview
Biotechnology : Current methods and recent advances in biological, medical, agricultural and engineering aspects of biotechnology will be described and discussed. An extensive reading list will complement the lecture material.
Terms: Fall 2011
Instructors: Vogel, Jacalyn (Fall)
Fall
Restriction: U3 students
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EXMD 401 Physiology and Biochemistry Endocrine Systems (3 credits)
Overview
Experimental Medicine : Offered in conjunction with the Department of Physiology. The course provides a basic knowledge of endocrine systems encompassing biosynthesis, metabolism and physiological actions of hormones. Specific topics covered are hormones of the hypothalamus, pituitary, adrenals, thyroids, parathyroids, pancreas, gut and the gonads. The role of hormones and growth factors in pregnancy and fetal development are also discussed.
Terms: Winter 2012
Instructors: Srikant, Coimbatore B (Winter)
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EXMD 502 Advanced Endocrinology 01 (3 credits)
Overview
Experimental Medicine : This course is designed for U3 students who are in a major or honours program in anatomy, biology, biochemistry or physiology and for graduate students. A multidisciplinary approach will be used to teach biosynthesis and processing of hormones, their regulation, function and mechanism of action. The material will cover hypothalamic, pituitary, thyroid, atrial and adrenal hormones as well as prostaglandins and related substances.
Terms: Fall 2011
Instructors: Bennett, Hugh P J; Bateman, Andrew (Fall)
Fall
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EXMD 503 Advanced Endocrinology 02 (3 credits)
Overview
Experimental Medicine : Study of the parathyroids, gut and pancreatic hormones and growth factors. In addition, the role of hormones and growth factors in reproduction and fetal maturation will be discussed.
Terms: Winter 2012
Instructors: Bennett, Hugh P J; Bateman, Andrew (Winter)
Winter
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EXMD 504 Biology of Cancer (3 credits)
Overview
Experimental Medicine : An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.
Terms: Fall 2011
Instructors: Thomson, David M P (Fall)
Fall
Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only
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EXMD 506 Advanced Applied Cardiovascular Physiology (3 credits)
Overview
Experimental Medicine : Offered in conjunction with the Department of Physiology. Current topics, methods and techniques for studying the cardiovascular system. Basic and applied cardiac electrophysiology, mechanisms of pacemaker activity, arrhythmias, the effects of drugs on cardiac functions, fetal circulation, coronary circulation, mechanics of blood flow, cardiovascular diseases, renal and neural control of the circulation, and cardiac assist devices.
Terms: Fall 2011
Instructors: Schwertani, Adel (Fall)
Fall
Prerequisite (Undergraduate): PHGY 313 or by permission of instructors
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EXMD 507 Advanced Applied Respiratory Physiology (3 credits)
Overview
Experimental Medicine : Offered in conjunction with the Department of Physiology. In depth coverage of respiratory biology including: functional anatomy of the respiratory system, pulmonary statics and dynamics, chest wall and respiratory muscles, ventilation and perfusion, control of breathing, and defense mechanisms. This course is aimed at providing a solid grounding in pulmonary biology and its research applications.
Terms: Fall 2011
Instructors: Petrof, Basil (Fall)
Fall
Prerequisite: PHGY 313
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EXMD 508 Advanced Topics in Respiration (3 credits)
Overview
Experimental Medicine : Offered in conjunction with the Department of Physiology. In depth coverage of developmental physiology, pulmonary vascular physiology, biology of airway smooth muscle, respiratory epithelium and molecular biology of respiratory muscles. Dyspnea, mechanical ventilation and respiratory failure will also be covered. This course emphasizes application of respiratory biology to basic and applied research and touches on pulmonary pathophysiology.
Terms: Winter 2012
Instructors: Fixman, Elizabeth Dee (Winter)
Winter
Prerequisite: EXMD 507
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MIMM 314 Immunology (3 credits)
Overview
Microbiology and Immun (Sci) : An introduction to the immune system, antigens, antibodies and lymphocytes. The course will cover the cellular and molecular basis of lymphocyte development and mechanisms of lymphocyte activation in immune responses.
Terms: Winter 2012
Instructors: Piccirillo, Ciriaco; Alizadehfar, Reza; Fournier, Sylvie (Winter)
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MIMM 323 Microbial Physiology (3 credits)
Overview
Microbiology and Immun (Sci) : An introduction to the composition and structure of microbial cells, the biochemical activities associated with cellular metabolism and how these activities are regulated and coordinated. The course will have a molecular and genetic approach to the study of microbial physiology.
Terms: Fall 2011
Instructors: Marczynski, Gregory T; Coulton, James W; Turcotte, Bernard (Fall)
Fall
3 hours of lecture
Prerequisite: MIMM 211
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MIMM 324 Fundamental Virology (3 credits)
Overview
Microbiology and Immun (Sci) : A study of the fundamental properties of viruses and their interactions with host cells. Bacteriophages, DNA- and RNA-containing animal viruses, and retroviruses are covered. Emphasis will be on phenomena occurring at the molecular level and on the regulated control of gene expression in virus-infected cells.
Terms: Fall 2011
Instructors: Gotte, Matthias; Teodoro, Jose Guerreiro; Liang, Chen (Fall)
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MIMM 387 The Business of Science (3 credits)
Overview
Microbiology and Immun (Sci) : The ability to select and manipulate genetic material has lead to unprecedented interest in the industrial applications of procaryotic and eucaryotic cells. Beginning in the 1970s the introduction of and subsequent refinements to recombinant DNA technology and hybridoma technology transformed the horizons of the biopharmaceutical world. This course will highlight the important events that link basic research to clinical/commercial application of new drugs and chemicals.
Terms: Winter 2012
Instructors: Murgita, Robert A; Bar-Or, Amit; Khoury, Lara (Winter)
Winter
Prerequisite: At least one 200-level course in a biological or biomedical discipline or permission of instructor
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MIMM 413 Parasitology (3 credits)
Overview
Microbiology and Immun (Sci) : A study of the biology, immunological aspects of host-parasite interactions, pathogenicity, epidemiology and molecular biological aspects of selected parasites of medical importance. Laboratory will consist of a lecture on techniques, demonstrations and practical work.
Terms: Winter 2012
Instructors: Matlashewski, Greg J; Olivier, Martin; Rohrbach, Petra (Winter)
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MIMM 414 Advanced Immunology (3 credits)
Overview
Microbiology and Immun (Sci) : An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.
Terms: Fall 2011
Instructors: Fournier, Sylvie; Olivier, Martin; Arbour, Nathalie (Fall)
Fall
3 hour lecture
Prerequisite: MIMM 314
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MIMM 465 Bacterial Pathogenesis (3 credits)
Overview
Microbiology and Immun (Sci) : Organized by the 91ÉçÇø Centre for the Study of Host Resistance. This course focuses on the interplay of the host and the pathogen. The cellular and molecular basis of the host defense mechanism against infections will be considered in relationship to the virulence factors and evasion strategies used by bacteria to cause disease.
Terms: Fall 2011
Instructors: Le-Moual, Herve; Olivier, Martin; Nguyen, Dao (Fall)
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MIMM 466 Viral Pathogenesis (3 credits)
Overview
Microbiology and Immun (Sci) : A study of the biological and molecular aspects of viral pathogenesis with emphasis on the human pathogenic viruses including the retroviruses HIV and HTLV-1; herpes viruses; papilloma viruses; hepatitis viruses; and new emerging human viral diseases. These viruses will be discussed in terms of virus multiplication, gene expression virus-induced cytopathic effects and host immune response to infection.
Terms: Winter 2012
Instructors: Gatignol, Anne; Liang, Chen; Wainberg, Mark (Winter)
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MIMM 509 Inflammatory Processes (3 credits)
Overview
Microbiology and Immun (Sci) : This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers (from 91ÉçÇø and other universities) and students will be furthered.
Terms: Winter 2012
Instructors: Rauch, Joyce Ellen; Di Battista, Giovanni; Bar-Or, Amit (Winter)
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NEUR 310 Cellular Neurobiology (3 credits)
Overview
Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.
Terms: Winter 2012
Instructors: Cloutier, Jean-Francois; Ragsdale, David S; Kennedy, Timothy E (Winter)
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PATH 300 Human Disease (3 credits)
Overview
Pathology : Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.
Terms: Winter 2012
Instructors: Zorychta, Edith; Richardson, John B (Winter)
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PHAR 300 Drug Action (3 credits)
Overview
Pharmacology and Therapeutics : Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.
Terms: Fall 2011
Instructors: Zorychta, Edith (Fall)
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PHAR 301 Drugs and Disease (3 credits)
Overview
Pharmacology and Therapeutics : This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.
Terms: Winter 2012
Instructors: Delbès, Géraldine; Clarke, Paul; Bowie, Derek (Winter)
Winter
Prerequisite: PHAR 300 or permission of instructor.
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PHAR 303 Principles of Toxicology (3 credits)
Overview
Pharmacology and Therapeutics : Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.
Terms: Winter 2012
Instructors: Culty, Martine; Zorychta, Edith; Delbès, Géraldine (Winter)
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PHAR 562 General Pharmacology 1 (3 credits)
Overview
Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular aspects and the nervous system; topics include molecular mechanisms of drug-action, cellular targets and rationale for therapeutics.
Terms: Fall 2011
Instructors: Almazan, Guillermina (Fall)
Fall
Prerequisite: PHAR 301.
Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
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PHAR 563 General Pharmacology 2 (3 credits)
Overview
Pharmacology and Therapeutics : Selected topics in pharmacology of the endocrine, metabolic, and cardiovascular systems. Additional topics include: pharmacogenetics/pharmacogenomics, chronopharmacology, molecular structure in pharmacology, epigenetic targets in cancer chemotherapy, and stem cell therapies.
Terms: Winter 2012
Instructors: Bernard, Daniel (Winter)
Winter
Prerequisite: PHAR 301.
Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
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PHGY 311 Channels, Synapses & Hormones (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.
Terms: Fall 2011
Instructors: Cooper, Ellis; Farookhi, Riaz; Haghighi, Ali (Fall)
Fall
3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term
Prerequisite: PHGY 209 or permission of the instructor.
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PHGY 312 Respiratory, Renal, & Cardiovascular Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.
Terms: Winter 2012
Instructors: Hanrahan, John W; Mortola, Jacopo; Shrier, Alvin (Winter)
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PHGY 313 Blood, Gastrointestinal, & Immune Systems Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.
Terms: Winter 2012
Instructors: Martinez Trujillo, Julio; Blank, Volker Manfred; Ponka, Premysl (Winter)
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PHGY 314 Integrative Neuroscience (3 credits)
Overview
Physiology : In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.
Terms: Fall 2011
Instructors: Cullen, Kathleen E; Martinez Trujillo, Julio; Pack, Christopher (Fall)
Fall
3 hours of lectures per week
Prerequisites: PHGY 209
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PHGY 451 Advanced Neurophysiology (3 credits)
Overview
Physiology : Topics of current interest in neurophysiology including the development of neurons and synapses, physiology of ionic channels, presynaptic and postsynaptic events in synaptic transmission and neuronal interactions in CNS function.
Terms: Fall 2011
Instructors: Cooper, Ellis; Cohen, Monroe W; Bourque, Charles W (Fall)
Fall
3 hours lecture
Prerequisite: PHGY 311 or equivalent
Restriction: Departmental approval required
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PHGY 502 Exercise Physiology (3 credits)
Overview
Physiology : Behaviour of physiological processes in response to physical effort, in areas such as structural basis of muscle contraction, thermoregulation during exercise, mechanics and energetics of muscle contraction, fuel utilization, fatigue, physiological adjustments during exercise and influence of training.
Terms: Winter 2012
Instructors: Lauzon, Anne-Marie; Comtois, Alain Steve; Martin, James G (Winter)
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PHGY 508 Advanced Renal Physiology (3 credits)
Overview
Physiology : Offered in conjunction with the Department of Medicine. Lectures and seminars will cover advanced concepts in selected areas of kidney physiology (glomerular and tubular function) as well as membrane and epithelial transport. Students will be expected to critically discuss selected experimental papers.
Terms: Fall 2011
Instructors: Cybulsky, Andrey V E; Iglesias, Diana Margarita; Podymow, Tiina (Fall)
Fall
Prerequisite (Undergraduate): PHGY 312 or the equivalent
Restriction: Open to advanced undergraduate and graduate students
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PHGY 513 Cellular Immunology (3 credits)
Overview
Physiology : This course deals with cellular interactions, regulation and effector mechanisms of the normal immune response in relation to diseases and pathogenic processes. It is taught at an advanced level.
Terms: Winter 2012
Instructors: Jones, Russell; Saleh, Maya; Behr, Marcel A (Winter)
Winter
3 hours lectures plus term paper
Prerequisite: MIMM 314, or permission of the instructor
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PHGY 515 Physiology of Blood 1 (3 credits)
Overview
Physiology : Study of the cell and molecular physiology of hemostasis and its pathophysiology (bleeding and thrombosis). Emphases on molecular mechanisms regulating clot formation, fibrinolysis, and cell adhesion/aggregation. Experimental approaches and specific clinical disorders will be analyzed. Weekly discussions, and a major term paper.
Terms: This course is not scheduled for the 2011-2012 academic year.
Instructors: There are no professors associated with this course for the 2011-2012 academic year.
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PHGY 516 Physiology of Blood 2 (3 credits)
Overview
Physiology : Bone marrow hematopoiesis, with emphasis on regulation of stem cell proliferation and differentiation along hematopoietic pathways. Formation and differentiation of red and white blood cells and some of the diseases associated with hematopoiesis will be covered. Emphasis will be given to the molecular mechanisms involved in the normal and pathological conditions.
Terms: Winter 2012
Instructors: Blank, Volker Manfred; Pantopoulos, Konstantinos; Ponka, Premysl (Winter)
Winter
2 hours lecture plus 1 hour seminar weekly
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PHGY 517 Artificial Internal Organs (3 credits)
Overview
Physiology : Physiological, bioengineering, chemical and clinical aspects of artificial organs including basic principles and physiopathology of organ failure. Examples: oxygenator, cardiac support, vascular substitutes, cardiac pacemaker, biomaterials and tissue engineering, biocompatibility.
Terms: This course is not scheduled for the 2011-2012 academic year.
Instructors: There are no professors associated with this course for the 2011-2012 academic year.
- Winter
- Prerequisite (Undergraduate): permission of instructors.
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PHGY 518 Artificial Cells (3 credits)
Overview
Physiology : Physiology, biotechnology, chemistry and biomedical application of artificial cells, blood substitutes, immobilized enzymes, microorganisms and cells, hemoperfusion, artificial kidneys, and drug delivery systems. PHGY 517 and PHGY 518 when taken together, will give a complete picture of this field. However, the student can select one of these.
Terms: Fall 2011
Instructors: Chang, Thomas Ming Swi; Prakash, Satya (Fall)
Fall
Prerequisite (Undergraduate): permission of instructors.
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PHGY 552 Cellular and Molecular Physiology (3 credits)
Overview
Physiology : Discussions of recent significant advances in our understanding of the gene products involved in diverse cellular signalling pathways. Topics will include cell-surface hormone receptors, nuclear steroid hormone receptors, and ion channels and transporters. Students will present and critically evaluate experimental approaches, results and interpretations of selected research publications.
Terms: Winter 2012
Instructors: Orlowski, John; White, John H; Stochaj, Ursula (Winter)
Winter
1 hour lecture, 2 hours seminar weekly
Prerequisite: PHGY 311
Preference will be given to Physiology Honours and Graduate students
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PHGY 556 Topics in Systems Neuroscience (3 credits)
Overview
Physiology : Topics of current interest in systems neurophysiology and behavioural neuroscience including: the neural representation of sensory information and motor behaviours, models of sensory motor integration, and the computational analysis of problems in motor control and perception. Students will be expected to present and critically discuss journal articles in class.
Terms: Winter 2012
Instructors: Cullen, Kathleen E; Guitton, Daniel E; Cook, Erik (Winter)
Winter
Restriction: Permission of the instructor required.
Restriction: Not open to students who have taken PHGY 456
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PSYT 455 Neurochemistry (3 credits)
Overview
Psychiatry : Covers biochemical mechanisms underlying central nervous system function. Introduces basic neuroanatomy, CNS cell types and morphology, neuronal excitability, chemically mediated transmission, glial function. Biochemistry of specific neurotransmitters, endocrine effects on brain, brain energy metabolism and cerebral ischemia (stroke). With examples, where relevant, of biochemical processes disrupted in human CNS disease.
Terms: Winter 2012
Instructors: Flores Parkman, Ana Cecilia; Mechawar, Naguib; Wong, Tak Pan (Winter)
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PSYT 500 Advances: Neurobiology of Mental Disorders (3 credits)
Overview
Psychiatry : Current theories on the neurobiological basis of most well known mental disorders (e.g. schizophrenia, depression, anxiety, dementia). Methods and strategies in research on genetic, physiological and biochemical factors in mental illness will be discussed. Discussion will also focus on the rationale for present treatment approaches and on promising new approaches.
Terms: Winter 2012
Instructors: Srivastava, Lalit K; Bruce, Kenneth Robert; Young, Simon N (Winter)
Winter
3 hours
Prerequisite (Undergraduate): BIOC 212 and BIOC 311, or BIOC 312, or BIOL 200 and BIOL 201, or PHGY 311, or PSYC 308 and an upper-level biological science course with permission of the instructors, or equivalent. Basic knowledge of cellular and molecular biology is required.
Restriction: Open to U3 and graduate students only.
Restriction: Graduate Studies: strongly recommended for M.Sc. students in Psychiatry.
Revision, August 2011. End of revision.
Faculty of Science—2011-2012 (last updated Jan. 26, 2012) (disclaimer)