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Program Requirements
The Honours program is designed as a preparation for graduate studies and research. In addition to the strong training provided by the Major program, it requires students to have direct research experience in a chosen area during their final year of study. Acceptance into the Honours program takes place in the Winter term of U2 and requires a CGPA of 3.50. Students who wish to enter the Honours program should follow the Major program; those who satisfactorily complete the first three terms with a CGPA of at least 3.50 and a mark of B+ or higher in core Pharmacology courses (PHAR 300, PHAR 301, and PHAR 303) are eligible for admission. Applications can be obtained from the office of the Department of Pharmacology in the McIntyre Medical Building or on the Departmental website.
U1 Required Courses (24 credits)
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BIOL 200 Molecular Biology (3 credits)
Overview
Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.
Terms: Fall 2016
Instructors: Zetka, Monique; Hastings, Kenneth E M; Roy, Richard D W; Lasko, Paul; Reyes Lamothe, Rodrigo (Fall)
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BIOL 202 Basic Genetics (3 credits)
Overview
Biology (Sci) : Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.
Terms: Winter 2017, Summer 2017
Instructors: Moon, Nam Sung; Nilson, Laura; Schoen, Daniel J (Winter) Dankort, David; Hipfner, David (Summer)
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CHEM 212 Introductory Organic Chemistry 1 (4 credits) *
Overview
Chemistry : A survey of reactions of aliphatic and aromatic compounds including modern concepts of bonding, mechanisms, conformational analysis, and stereochemistry.
Terms: Fall 2016, Winter 2017, Summer 2017
Instructors: Daoust, Michel; Gauthier, Jean-Marc; Huot, Mitchell; Sleiman, Hanadi; Pavelka, Laura (Fall) Lumb, Jean-Philip; Pavelka, Laura; Daoust, Michel; Gauthier, Jean-Marc (Winter) Pavelka, Laura; Daoust, Michel (Summer)
Fall, Winter, Summer
Prerequisite: CHEM 110 or equivalent.
Corequisite: CHEM 120 or equivalent.
Restriction: Not open to students who are taking or have taken CHEM 211 or equivalent
Each lab section is limited enrolment
Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page ().
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CHEM 222 Introductory Organic Chemistry 2 (4 credits) *
Overview
Chemistry : Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.
Terms: Fall 2016, Winter 2017, Summer 2017
Instructors: Daoust, Michel; Gauthier, Jean-Marc; Huot, Mitchell; Perepichka, Dmytro (Fall) Pavelka, Laura; Daoust, Michel; Gauthier, Jean-Marc; Li, Chaojun (Winter) Pavelka, Laura; Daoust, Michel (Summer)
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PHAR 200 Introduction to Pharmacology 1 (1 credit)
Overview
Pharmacology and Therapeutics : The objective of this course is to give U1 Pharmacology Major program students an appreciation of research in Pharmacology. The focus will be on contributions of this research to our understanding of how drugs work, strategies towards the discovery of new drugs, and/or on how use of current drugs may be improved based on this understanding.
Terms: Fall 2016
Instructors: Hales, Barbara F; Trempe, Jean Francois; Maysinger, Dusica (Fall)
Restriction(s): Only open to students in the BSc. Major in Pharmacology.
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PHAR 201 Introduction to Pharmacology 2 (1 credit)
Overview
Pharmacology and Therapeutics : This course will be a continuation of PHAR 200, taught in the fall semester. The focus will be on contributions of this research to our understanding of how drugs work, strategies towards the discovery of new drugs, and/or on how use of current drugs may be improved based on this understanding.
Terms: Winter 2017
Instructors: Hales, Barbara F; Robaire, Bernard; Nattel, Stanley (Winter)
Prerequisite(s): PHAR 200
Restriction(s): Only open to students in the BSc. Major in Pharmacology.
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PHGY 209 Mammalian Physiology 1 (3 credits)
Overview
Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.
Terms: Fall 2016
Instructors: Vollrath, Melissa; Gold, Phil; Wechsler, Ann (Fall)
Fall
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
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PHGY 210 Mammalian Physiology 2 (3 credits)
Overview
Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.
Terms: Winter 2017
Instructors: White, John H; Campeau, Lysanne; Takano, Tomoko (Winter)
Winter
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisite: BIOL 200, BIOL 201, BIOC 212, CHEM 212 or equivalent.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
Although PHGY 210 may be taken without the prior passing of PHGY 209, students should note that they may have some initial difficulties because of lack of familiarity with some basic concepts introduced in PHGY 209
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PHGY 212 Introductory Physiology Laboratory 1 (1 credit)
Overview
Physiology : Exercises illustrating fundamental principles in physiology: Biological Signals Acquisitions, Blood, Immunology, Neurophysiology, Neuromuscular Physiology.
Terms: Fall 2016
Instructors: Vollrath, Melissa; Glavinovic, Mladen I; Bernard, Nicole F; Mandl, Judith (Fall)
(One 3-hour lab and one 1-hour lecture every second week.)
Corequisite: PHGY 209.
Restrictions: Required for Physiology students enrolled in PHGY 209. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
Note: For students in a Physiology program, PHGY 212 should be taken concurrently with PHGY 209.
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PHGY 213 Introductory Physiology Laboratory 2 (1 credit)
Overview
Physiology : Exercises illustrating fundamental principles in physiology: Central Nervous System, Cardiovascular, Respiration, Exercise Physiology, Molecular Endocrinology.
Terms: Winter 2017
Instructors: Guevara, Michael R; Mortola, Jacopo; Watt, Douglas; Magder, Sheldon A (Winter)
(One 3-hour lab and one 1-hour lecture every second week.)
Prerequisite: PHGY 212
Corequisite: PHGY 210.
Restrictions: Required for Physiology students enrolled in PHGY 210. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
Note: For students in a Physiology program, PHGY 213 should be taken concurrently with PHGY 210.
* Students who have taken the equivalent of CHEM 212, CHEM 222,and/or MATH 203 in CEGEP (as defined at: ) are exempt and may not take these courses at 91社区. Students must replace these credits with appropriate complementary course credits to satisfy the total credit requirements for their degree.
U2 Required Courses (16 credits)
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BIOC 311 Metabolic Biochemistry (3 credits)
Overview
Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.
Terms: Fall 2016
Instructors: St-Pierre, Julie; Schmeing, Thomas Martin; Tremblay, Michel (Fall)
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BIOL 301 Cell and Molecular Laboratory (4 credits)
Overview
Biology (Sci) : An introduction to laboratory techniques with a focus on methods used to investigate fundamental questions in modern cell and molecular biology. Techniques including gene cloning, DNA and protein isolation and manipulation are covered, along with functional analysis of genes and proteins, basic bioinformatics, and computer-based experimental design and data analysis.
Terms: Fall 2016, Winter 2017
Instructors: Zheng, Huanquan; Harrison, Paul; Reyes Lamothe, Rodrigo (Fall) Zheng, Huanquan; Harrison, Paul; Reyes Lamothe, Rodrigo (Winter)
Fall or Winter
1 hour lecture and one 6-hour laboratory
Prerequisites: PHYS 102 or PHYS 142, BIOL 200, BIOL 201 or ANAT/BIOC 212, and BIOL 202. BIOL 206 recommended.
Restrictions: Not open to students who have taken or are taking BIOC 300. Requires departmental approval.
For approval email anne-marie.sdicu [at] mcgill.ca. Specify your ID number as well as the term and two lab day preferences.
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PHAR 300 Drug Action (3 credits)
Overview
Pharmacology and Therapeutics : Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.
Terms: Fall 2016
Instructors: Zorychta, Edith; Hales, Barbara F (Fall)
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PHAR 301 Drugs and Disease (3 credits)
Overview
Pharmacology and Therapeutics : This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.
Terms: Winter 2017
Instructors: Hales, Barbara F; Clarke, Paul; Szyf, Moshe (Winter)
Winter
Prerequisite: PHAR 300
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PHAR 303 Principles of Toxicology (3 credits)
Overview
Pharmacology and Therapeutics : Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.
Terms: Winter 2017
Instructors: Robaire, Bernard; Hales, Barbara F; Zorychta, Edith (Winter)
U3 Required Courses (6 credits)
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PHAR 598D1 Honours Pharmacology Research Project (3 credits)
Overview
Pharmacology and Therapeutics : Supervised Honours Research Project in Pharmacology. Students are expected to obtain hands-on research experience in their supervisor's laboratory. They are also required to submit a written report in the form of a scientific manuscript and present a ten minute seminar.
Terms: Fall 2016, Summer 2017
Instructors: McKinney, R. Anne; Maysinger, Dusica (Fall) McKinney, R. Anne; Maysinger, Dusica (Summer)
Corequisite(s): PHAR 562 General Pharmacology 1
Corequisite(s): PHAR 563 General Pharmacology 2
Restriction(s): Only open to U3 students accepted in the BSc. Honours Pharmacology. Requires Departmental approval.
Students must register for both PHAR 598 D1 and PHAR 598 D2.
No credit will be given for this course unless both PHAR 598 D1 and PHAR 598 D2 are successfully completed in consecutive terms.
Minimum of 9 hours/week to be spent in the lab.
A statement of the proposed project and method of evaluation, signed by the student and supervisor, must be submitted to the departmental Director of Undergraduate Studies for approval by the add/drop deadline of the semester in which the student registers for this course.
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PHAR 598D2 Honours Pharmacology Research Project (3 credits)
Overview
Pharmacology and Therapeutics : See PHAR 598D1 for course description.
Terms: Winter 2017
Instructors: Maysinger, Dusica; McKinney, R. Anne (Winter)
Prerequisite(s): PHAR 598D1
Students must register for both PHAR 598 D1 and PHAR 598 D2.
No credit will be given for this course unless both PHAR 598 D1 and PHAR 598 D2 are successfully completed in consecutive terms.
Complementary Courses (30 credits)
15 credits selected as follows:
3 credits selected from (usually in Year 1):
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ANAT 212 Molecular Mechanisms of Cell Function (3 credits)
Overview
Anatomy & Cell Biology : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.
Terms: Winter 2017
Instructors: Pause, Arnim; Bouchard, Maxime; Young, Jason (Winter)
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BIOC 212 Molecular Mechanisms of Cell Function (3 credits)
Overview
Biochemistry : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.
Terms: Winter 2017
Instructors: Pause, Arnim; Bouchard, Maxime; Young, Jason (Winter)
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BIOL 201 Cell Biology and Metabolism (3 credits)
Overview
Biology (Sci) : This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle.
Terms: Winter 2017
Instructors: Brouhard, Gary (Winter)
3 credits selected from (usually in Year 2):
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CHEM 203 Survey of Physical Chemistry (3 credits)
Overview
Chemistry : The fundamentals of thermodynamics and chemical kinetics with applications to biomolecular systems. Thermodynamic and kinetic control of biological processes.
Terms: Fall 2016
Instructors: Sanctuary, Bryan Clifford (Fall)
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CHEM 204 Physical Chemistry/Biological Sciences 1 (3 credits)
Overview
Chemistry : Similar to CHEM 223/CHEM 243. Emphasis on the use of biological examples to illustrate the principles of physical chemistry. The relevance of physical chemistry to biology is stressed.
Terms: Fall 2016, Winter 2017
Instructors: Kambhampati, Patanjali (Fall) Sanctuary, Bryan Clifford; Sewall, Samuel Lewis; Kambhampati, Patanjali (Winter)
3 credits selected from (usually in Year 2):
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BIOL 373 Biometry (3 credits)
Overview
Biology (Sci) : Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages.
Terms: Fall 2016
Instructors: Leung, Brian (Fall)
Fall
2 hours lecture and 2 hours laboratory
Prerequisite: MATH 112 or equivalent
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
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MATH 203 Principles of Statistics 1 (3 credits) *
Overview
Mathematics & Statistics (Sci) : Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions).
Terms: Fall 2016, Winter 2017, Summer 2017
Instructors: Steele, Russell; Schulz, Juliana (Fall) Yang, Yi (Winter) Correa, Jose Andres (Summer)
No calculus prerequisites
Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult for information regarding transfer credits for this course.
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PSYC 204 Introduction to Psychological Statistics (3 credits)
Overview
Psychology : The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance.
Terms: Fall 2016, Winter 2017, Summer 2017
Instructors: Amsel, Rhonda N (Fall) Darainy, Mohammad; Sadikaj, Gentiana (Winter) Darainy, Mohammad (Summer)
Fall and Winter
Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300
This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
3 credits selected from (usually in Year 3):
- PHAR 503 Drug Discovery and Development 1 (3 credits)
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PHAR 505 Structural Pharmacology (3 credits)
Overview
Pharmacology and Therapeutics : The course will cover approaches widely used in the pharmaceuticals industry, such as drug target selection, structure determination and medicinal chemistry. The basics of structural biology will be taught in a very visual and interactive manner, with an emphasis on drug:target interactions and chemical principles relevant to drug design. By the end of the course, the students will become familiar with the structure-based drug discovery process and principles of molecular pharmacology.
Terms: Fall 2016
Instructors: Trempe, Jean Francois; Castagner, Bastien (Fall)
3 credits selected from (usually in Year 3):
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PHAR 562 Neuropharmacology (3 credits)
Overview
Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular mechanisms of drug-action and cellular targets in the nervous system.
Terms: Fall 2016
Instructors: Bowie, Derek; Trempe, Jean Francois; Clarke, Paul (Fall)
Fall
Prerequisite: PHAR 301 or with permission of instructor.
Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
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PHAR 563 Endocrine Pharmacology (3 credits)
Overview
Pharmacology and Therapeutics : This advanced course covers selected topics in pharmacology of reproductive, endocrine, and metabolic disorders.
Terms: Winter 2017
Instructors: Bernard, Daniel; Goodyer, Cynthia; Robaire, Bernard (Winter)
Prerequisite: PHAR 301 or permission of the instructor(s)
Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
Course material will be presented in the form of lectures and student-led presentations.
15 credits selected from the following upper-level science courses:
Committee approval is required to substitute an upper-level science course not in the list below.
* Note: Students may take either ANAT 458 or BIOC 458.
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ANAT 321 Circuitry of the Human Brain (3 credits)
Overview
Anatomy & Cell Biology : This course explores the functional organization of the human brain and spinal cord. The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations.
Terms: Fall 2016
Instructors: Ragsdale, David S (Fall)
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ANAT 322 Neuroendocrinology (3 credits)
Overview
Anatomy & Cell Biology : A lecture course describing brain-endocrine relationships. Emphasis on modern experimental evidence and conceptual developments within the field.
Terms: Winter 2017
Instructors: Walker, Claire; Stroh, Thomas; Tamilia, Michael (Winter)
Winter
3 hours lecture
Prerequisite: ANAT 261.
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ANAT 365 Cellular Trafficking (3 credits)
Overview
Anatomy & Cell Biology : An intensive study of the processes of protein secretion and cell membrane biogenesis. Emphasis on morphological aspects of the above processes, and on the major techniques which have provided experimental evidence, namely, subcellular fractionation, cytochemistry and quantitative electron microscope radioautography.
Terms: Fall 2016
Instructors: McBride, Heidi; McPherson, Peter Scott; Kennedy, Timothy E (Fall)
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ANAT 458 Membranes and Cellular Signaling (3 credits) *
Overview
Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2017
Instructors: Silvius, John R; Autexier, Chantal; Lamarche, Nathalie (Winter)
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BIOC 312 Biochemistry of Macromolecules (3 credits)
Overview
Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).
Terms: Winter 2017
Instructors: Huang, Sidong; Richard, Stephane; Pelletier, Gerard (Winter)
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BIOC 450 Protein Structure and Function (3 credits)
Overview
Biochemistry : Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.
Terms: Fall 2016
Instructors: Nagar, Bhushan; Schmeing, Thomas Martin; Purisima, Enrico (Fall)
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BIOC 454 Nucleic Acids (3 credits)
Overview
Biochemistry : RNA processing, localization and stability. RNAi mechanisms, regulation and applications. Regulation of DNA replication. Genomics: human genome sequence, regulation and organization. DNA repair mechanisms. Special topics on transgenics, genetic diseases and cancer.
Terms: Fall 2016
Instructors: Dostie, Josee; Teodoro, Jose Guerreiro; Sonenberg, Nahum (Fall)
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BIOC 458 Membranes and Cellular Signaling (3 credits) *
Overview
Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2017
Instructors: Silvius, John R; Autexier, Chantal; Lamarche, Nathalie (Winter)
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BIOL 300 Molecular Biology of the Gene (3 credits)
Overview
Biology (Sci) : A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.
Terms: Fall 2016
Instructors: Sch枚ck, Frieder; Moon, Nam Sung (Fall)
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BIOL 303 Developmental Biology (3 credits)
Overview
Biology (Sci) : A consideration of the fundamental processes and principles operating during embryogenesis. Experimental analyses at the molecular, cellular, and organismal levels will be presented and discussed to provide an overall appreciation of developmental phenomena.
Terms: Winter 2017
Instructors: Hendricks, Shelton; Rao, Yong; Dufort, Daniel (Winter)
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BIOL 306 Neural Basis of Behaviour (3 credits)
Overview
Biology (Sci) : Neural mechanisms of animal behaviour; neuroethology; cellular neurophysiology, integrative networks within nervous systems; neural control of movement; processing of sensory information.
Terms: Fall 2016
Instructors: Watt, Alanna; Sakata, Jon (Fall)
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BIOL 314 Molecular Biology of Oncogenes (3 credits)
Overview
Biology (Sci) : The genes that cause cancer are altered versions of genes present in normal cells. The origins of these oncogenes, their genetic structure, regulation, and the biochemical properties of the oncogene-encoded proteins will be analyzed in an attempt to understand the origins of human and animal cancers.
Terms: Fall 2016
Instructors: Majewska, Loydie; Christensen, Karen Elizabeth; Tonin, Patricia N (Fall)
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BIOT 505 Selected Topics in Biotechnology (3 credits)
Overview
Biotechnology : Current methods and recent advances in biological, medical, agricultural and engineering aspects of biotechnology will be described and discussed. An extensive reading list will complement the lecture material.
Terms: Fall 2016
Instructors: Georges, Elias; Chitramuthu, Babykumari; Chang, Thomas Ming Swi (Fall)
Fall
Restriction: U3 students
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CHEM 302 Introductory Organic Chemistry 3 (3 credits)
Overview
Chemistry : Topics covered may include the following: Aromatic compounds, heterocyclic chemistry, sulfur and phosphorus chemistry, organosulfur and organophosphorus compounds, and biomolecules such as lipids, carbohydrates, amino acids, polypeptides, DNA and RNA.
Terms: Fall 2016
Instructors: Gleason, James L; Damha, Masad J (Fall)
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CHEM 334 Advanced Materials (3 credits)
Overview
Chemistry : The physicochemical properties of advanced materials. Topics discussed include photonics, information storage, 'smart' materials, biomaterials, clean energy materials, porous materials, and polymers.
Terms: Fall 2016
Instructors: Friscic, Tomislav (Fall)
Fall
Prerequisites: CHEM 110/CHEM 120 and PHYS 101/PHYS 102 or PHYS 131/PHYS 142, or CEGEP Physics and Chemistry, or equivalent. Prerequisite or Corerequisite: one of CHEM 203, CHEM 204, CHEM 223 and CHEM 243, CHEM 214 or equivalent; or one of PHYS 230 and PHYS 232, or equivalent; or permission of instructor.
Restriction: Not open to students who have taken or are taking PHYS 334.
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CHEM 482 Organic Chemistry: Natural Products (3 credits)
Overview
Chemistry : Structure, synthesis, stereochemistry and biosynthesis of terpenes, alkaloids, antibiotics and selected molecules of medicinal interest.
Terms: Winter 2017
Instructors: Tsantrizos, Youla S (Winter)
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CHEM 502 Advanced Bio-Organic Chemistry (3 credits)
Overview
Chemistry : This course will cover biologically relevant molecules, particularly nucleic acids, proteins, and their building blocks. In each case, synthesis and biological functions will be discussed. The topics include synthesis of oligonucleotides and peptides; chemistry of phosphates; enzyme structure and function; coenzymes, and enzyme catalysis; polyketides; antiviral and anticancer agents.
Terms: Winter 2017
Instructors: Thibodeaux, Christopher; Wahba, Alexander (Winter)
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CHEM 503 Drug Discovery (3 credits)
Overview
Chemistry : The aim of this course is to provide an introduction to the overall drug discovery process. The main focus of the course will be on medicinal chemistry, synthesis and catalysis, as they relate to large-scale production of pharmaceutical agents. However, other aspects of drug discovery, including structural research (e.g. NMR, X-ray), biochemistry, drug metabolism and bioavailability will also be included.
Terms: Fall 2016
Instructors: Tsantrizos, Youla S (Fall)
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CHEM 504 Drug Design (3 credits)
Overview
Chemistry : Computational methods used in drug design and discovery including QSAR, docking/scoring, molecular mechanics and molecular dynamics, QM/MM, library profiling and library design.
Terms: This course is not scheduled for the 2016-2017 academic year.
Instructors: There are no professors associated with this course for the 2016-2017 academic year.
Winter
Prerequisite: CHEM 503 and permission of instructor
Restriction: U3 and graduate students. Students can register only with permission of coordinators
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CHEM 522 Stereochemistry (3 credits)
Overview
Chemistry : Stereoisomers, their nomenclature and configuration. Conformational analysis, separation of stereoisomers, and stereocontrol in organic synthesis.
Terms: This course is not scheduled for the 2016-2017 academic year.
Instructors: There are no professors associated with this course for the 2016-2017 academic year.
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CHEM 552 Physical Organic Chemistry (3 credits)
Overview
Chemistry : The correlation of theory with physical measurements on organic systems; an introduction to photochemistry; solvent and substituent effects on organic reaction rates, etc.; reaction mechanisms.
Terms: Winter 2017
Instructors: Perepichka, Dmytro (Winter)
Winter
Prerequisite: CHEM 302
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EXMD 401 Physiology and Biochemistry Endocrine Systems (3 credits)
Overview
Experimental Medicine : Offered in conjunction with the Department of Physiology. The course provides a basic knowledge of endocrine systems encompassing biosynthesis, metabolism and physiological actions of hormones. Specific topics covered are hormones of the hypothalamus, pituitary, adrenals, thyroids, parathyroids, pancreas, gut and the gonads. The role of hormones and growth factors in pregnancy and fetal development are also discussed.
Terms: Winter 2017
Instructors: Liu, Jun-Li (Winter)
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EXMD 504 Biology of Cancer (3 credits)
Overview
Experimental Medicine : An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.
Terms: Fall 2016
Instructors: Topisirovic, Ivan; Fabian, Marc (Fall)
Fall
Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only
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EXMD 511 Joint Venturing with Industry (3 credits)
Overview
Experimental Medicine : Using problem-based learning, the course examines the various business interactions between researchers and their business partners in support and development of research into commercial endeavours using models such as venture capital, business partnerships, or grants-in-aid.
Terms: This course is not scheduled for the 2016-2017 academic year.
Instructors: There are no professors associated with this course for the 2016-2017 academic year.
Winter
Offered in conjunction with the Centre for Continuing Education
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MIMM 387 The Business of Science (3 credits)
Overview
Microbiology and Immun (Sci) : The ability to select and manipulate genetic material has led to unprecedented interest in the industrial applications of procaryotic and eucaryotic cells. Beginning in the 1970s the introduction of and subsequent refinements to recombinant DNA technology and hybridoma technology transformed the horizons of the biopharmaceutical world. This course will highlight the important events that link basic research to clinical/commercial application of new drugs and chemicals.
Terms: Winter 2017
Instructors: Murgita, Robert A; Antel, Jack P; Ward, Brian (Winter)
Winter
Prerequisite: At least one 200-level course in a biological or biomedical discipline or permission of instructor
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MIMM 414 Advanced Immunology (3 credits)
Overview
Microbiology and Immun (Sci) : An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.
Terms: Fall 2016
Instructors: Fritz, J枚rg; Richer, Martin; Krawczyk, Connie (Fall)
Fall
3 hour lecture
Prerequisite: MIMM 314
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NEUR 310 Cellular Neurobiology (3 credits)
Overview
Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.
Terms: Winter 2017
Instructors: Cloutier, Jean-Francois; Ragsdale, David S; Kennedy, Timothy E (Winter)
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PATH 300 Human Disease (3 credits)
Overview
Pathology : Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.
Terms: Winter 2017
Instructors: Zorychta, Edith (Winter)
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PHAR 390 Laboratory in Pharmacology (3 credits)
Overview
Pharmacology and Therapeutics : This course is a two-week all day practical laboratory course where students will have the opportunity to design their own experiments, write out the experimental lab reports and learn to trouble shoot on their own.
Terms: Summer 2017
Instructors: Munter, Lisa (Summer)
Restriction(s): Restricted to Pharmacology Honours students, or permission of instructor.
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PHAR 504 Drug Discovery and Development 2 (3 credits)
Overview
Pharmacology and Therapeutics : Nobel Prize-winning discoveries as a basis for drug development.
Terms: Winter 2017
Instructors: Maysinger, Dusica; Castagner, Bastien (Winter)
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PHAR 508 Drug Discovery and Development 3 (3 credits)
Overview
Pharmacology and Therapeutics : The design of biologically-relevant drug screens for molecular targets in a cell, tissue, and in vivo setting. Explore the use of stem cells and tissue-based disease models for the understanding of disease and for drug discovery. Situate modern pharmacology into broader medical and societal issues such as personalized medicine and the ethics associated with research.
Terms: Winter 2017
Instructors: Hebert, Terence; Trempe, Jean Francois; Clarke, Paul (Winter)
Prerequisite(s): PHAR 301 (PHAR 503 or PHAR 505 are also highly recommended)
Restriction(s): Open to U3 students in the minor, major or honours program in Pharmacology.
Not open to students who have taken PHAR 558.
Assessment modalities- in class presentations and discussion, take-home exams and writing exercises.
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PHAR 562 Neuropharmacology (3 credits)
Overview
Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular mechanisms of drug-action and cellular targets in the nervous system.
Terms: Fall 2016
Instructors: Bowie, Derek; Trempe, Jean Francois; Clarke, Paul (Fall)
Fall
Prerequisite: PHAR 301 or with permission of instructor.
Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
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PHAR 563 Endocrine Pharmacology (3 credits)
Overview
Pharmacology and Therapeutics : This advanced course covers selected topics in pharmacology of reproductive, endocrine, and metabolic disorders.
Terms: Winter 2017
Instructors: Bernard, Daniel; Goodyer, Cynthia; Robaire, Bernard (Winter)
Prerequisite: PHAR 301 or permission of the instructor(s)
Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
Course material will be presented in the form of lectures and student-led presentations.
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PHAR 565 Epigenetic Drugs and Targets (3 credits)
Overview
Pharmacology and Therapeutics : This course covers therapeutics targeting epigenetic mechanisms. Although only a handful of epigenetic drugs are in widespread use, further development of such agents is a very active area of research as it has the potential to directly target aberrant gene expression. This course will examine both the current use and potential of epigenetic drugs in treatment of cancer, neurological diseases, immune disorders, and cardiovascular disease. The concept of epigenetics as mediating gene-environment interaction will also be discussed.
Terms: Winter 2017
Instructors: Tanny, Jason; Trasler, Jacquetta M; Szyf, Moshe (Winter)
Prerequisite(s): PHAR 301.
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PHGY 311 Channels, Synapses & Hormones (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.
Terms: Fall 2016
Instructors: Cooper, Ellis; Sjostrom, Per Jesper; Sharif Naeini, Reza (Fall)
Fall
3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term
Prerequisite: PHGY 209 or permission of the instructor.
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PHGY 312 Respiratory, Renal, & Cardiovascular Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.
Terms: Winter 2017
Instructors: Hanrahan, John W; Mortola, Jacopo; Shrier, Alvin (Winter)
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PHGY 313 Blood, Gastrointestinal, & Immune Systems Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.
Terms: Winter 2017
Instructors: Jones, Russell; Blank, Volker Manfred; Kokoeva, Maia (Winter)
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PHGY 314 Integrative Neuroscience (3 credits)
Overview
Physiology : In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.
Terms: Fall 2016
Instructors: Chacron, Maurice; Sharif Naeini, Reza; Cook, Erik (Fall)
Fall
3 hours of lectures per week
Prerequisites: PHGY 209
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PHGY 520 Ion Channels (3 credits)
Overview
Physiology : A discussion of the principal theories and interesting new developments in the study of ion channels. Based on a textbook, computer exercises and critical reading and presentation of research papers. Topics include: Properties of voltage-and ligand-gated channels, single channel analysis, structure and function of ion channels.
Terms: Fall 2016
Instructors: Sharif Naeini, Reza; Ragsdale, David S; Cooper, Ellis (Fall)
Winter
Offered in even numbered years
1 1/2 hour lecture, 1 1/2 hour seminar
Prerequisite: PHGY 311
Priority to Graduate and Honours students; others by permission of instructors.
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PPHS 501 Population Health and Epidemiology (3 credits)
Overview
PPHS : This course presents concepts and methods of epidemiology at the introductory level. The use of epidemiologic methods for population and public health research and practice will be illustrated. A review of selected population health questions such as the HIV/AIDS epidemic, the cardiovascular disease epidemic, cigarette smoking, or screening for disease will be presented.
Terms: Winter 2017
Instructors: Maheu-Giroux, Mathieu (Winter)
Restriction(s): Not open to students who have taken EPIB 501.
Course not open to students enrolled in Epidemiology or Public Health programs.
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PSYC 302 The Psychology of Pain (3 credits)
Overview
Psychology : An introduction to pain research and theory, with emphasis on the interactions of psychological, cultural and physiological factors in pain perception. The role of these factors in clinical pain and its management by pharmacological and non-pharmacological means will be discussed.
Terms: Fall 2016
Instructors: Mogil, Jeffrey (Fall)
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PSYC 311 Human Cognition and the Brain (3 credits)
Overview
Psychology : The course is an introduction to the field studying how human cognitive processes, such as perception, attention, language, learning and memory, planning and organization, are related to brain processes. The material covered is primarily based on studies of the effects of different brain lesions on cognition and studies of brain activity in relation to cognitive processes with modern functional neuroimaging methods.
Terms: Fall 2016, Summer 2017
Instructors: Petrides, Michalakis (Fall) Petrides, Michalakis (Summer)
Fall
2 lectures; 1 conference
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PSYT 301 Issues in Drug Dependence (3 credits)
Overview
Psychiatry : The phenomenology and epidemiology of the use and abuse of alcohol, nicotine, opiates, stimulants, sedatives and psychotomimetic agents are discussed in relation to current theoretical and experimental issues. The perspective is multidisciplinary and the intention is to develop an understanding of the nature of the issues surrounding drug dependence.
Terms: This course is not scheduled for the 2016-2017 academic year.
Instructors: There are no professors associated with this course for the 2016-2017 academic year.
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PSYT 455 Neurochemistry (3 credits)
Overview
Psychiatry : Covers biochemical mechanisms underlying central nervous system function. Introduces basic neuroanatomy, CNS cell types and morphology, neuronal excitability, chemically mediated transmission, glial function. Biochemistry of specific neurotransmitters, endocrine effects on brain, brain energy metabolism and cerebral ischemia (stroke). With examples, where relevant, of biochemical processes disrupted in human CNS disease.
Terms: Winter 2017
Instructors: Flores Parkman, Ana Cecilia; Chakravarty, Megha; Wong, Tak Pan (Winter)
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PSYT 500 Advances: Neurobiology of Mental Disorders (3 credits)
Overview
Psychiatry : Current theories on the neurobiological basis of most well known mental disorders (e.g. schizophrenia, depression, anxiety, dementia). Methods and strategies in research on genetic, physiological and biochemical factors in mental illness will be discussed. Discussion will also focus on the rationale for present treatment approaches and on promising new approaches.
Terms: Winter 2017
Instructors: Wong, Tak Pan; Chakravarty, Megha; Mechawar, Naguib (Winter)
Winter
3 hours
Prerequisite (Undergraduate): BIOC 212 and BIOC 311, or BIOC 312, or BIOL 200 and BIOL 201, or PHGY 311, or PSYC 308 and an upper-level biological science course with permission of the instructors, or equivalent. Basic knowledge of cellular and molecular biology is required.
Restriction: Open to U3 and graduate students only.
Restriction: Graduate Studies: strongly recommended for M.Sc. students in Psychiatry.
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REDM 410 Writing Research Articles (3 credits)
Overview
Redpath Museum : Students will learn about the scientific article, publishing in the sciences, and the benefits of writing for a wide audience. This course focuses on how to structure the Abstract, as well as the Introduction and Discussion section of the full manuscript, and on editing techniques.
Terms: This course is not scheduled for the 2016-2017 academic year.
Instructors: There are no professors associated with this course for the 2016-2017 academic year.
Prerequisite: 24 credits of 200/300-level Science courses.
Restriction: This is an advanced course and permission of the instructor is required. To obtain permission, students should email the instructor, linda.cooper [at] mcgill.ca. Not open to students who are taking or have taken REDM 399.
Faculty of Science—2016-2017 (last updated Aug. 26, 2016) (disclaimer)