Program Requirements
Biomedical engineering can be defined as the application of engineering principles to medicine and the life sciences. Students in the Biomedical Engineering Minor take courses in life sciences (anatomy, biology, chemistry, and physiology) and choose courses form area(s) within the field of biomedicine (artificial cells and organs; bioinformatics, genomics, and proteomics; biomaterials, biosensors, and nanotechnology; biomechanics and prosthetics; medical physics and imagine; neural systems and biosignal processesing).
Note: Open to students in the Faculty of Engineering and the Department of Bioresource Engineering.
The Biomedical Engineering Minor allows access to courses in basic life sciences and it intended to expose students to the interdisciplinary tools used in biomedicine.
To complete this Minor, students must obtain a grade of C or better in all approved courses and satisfy the requirements of both the major program and the Minor. By careful selection of courses, the Minor can be satisfied with 9 additional credits in the student's major program or a maximum of 12 credits overlap with the major program.
Students considering this Minor should contact the Minor Advisers listed above.
Minor Advisers: Prof. R. Leask (Wong Building, Room 4120), Prof. R. Mongrain (Macdonald Engineering Building, Room 369) or Prof. G. Mitsis (McConnell Engineering Building, Room 361).
Complementary Courses
(21-25 credits)
Introductory Life Sciences
Minimum of 3 credits from the courses below:
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ANAT 212 Molecular Mechanisms of Cell Function (3 credits) *
Overview
Anatomy & Cell Biology : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.
Terms: Winter 2025
Instructors: Vera Ugalde, Maria; Reinhardt, Dieter; Fabian, Marc; Kiss, Robert; Pastor, William (Winter)
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BIEN 219 Introduction to Physical Molecular
and Cell Biology (4 credits) **
Overview
BIEN : An introduction to molecular and cell biology from a physical perspective. Techniques and methodologies, both experimental and computational, are included in the presentation of each thematic module.
Terms: Fall 2024
Instructors: Hendricks, Adam; Watt, Alanna; Reyes Lamothe, Rodrigo; Weber, Stephanie (Fall)
Corequisite(s): MATH 222 or equivalent
Prerequisite(s): BIOL 112; CHEM 110 and CHEM 120; MATH 140, MATH 141 and MATH 133; PHYS 131 and PHYS 142; or the equivalents of these courses
Restriction(s): Not open to students who have taken or are taking ANAT212, BIOC212, BIOL200, BIOL 201 and BIOL219. Only open to students in Bioengineering, Computer Science-Biology, Biology-Mathematics, BiologyQuantitative Biology, Chemistry-Biophysical Chemistry, and Physics-Biological Physics options.
This course is meant to prepare students for related 300-level courses in Biology, Chemistry, Engineering, and Physics.
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BIOC 212 Molecular Mechanisms of Cell Function (3 credits) *
Overview
Biochemistry : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.
Terms: Winter 2025
Instructors: Vera Ugalde, Maria; Pause, Arnim; Reinhardt, Dieter; Kazak, Lawrence; Cockburn, Katie (Winter)
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BIOL 200 Molecular Biology (3 credits)
Overview
Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.
Terms: Fall 2024
Instructors: Champetier, Serge; Hastings, Kenneth E M; Lasko, Paul; Turney, Shaun; Reyes Lamothe, Rodrigo (Fall)
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BIOL 201 Cell Biology and Metabolism (3 credits) *
Overview
Biology (Sci) : This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle.
Terms: Winter 2025
Instructors: Brouhard, Gary; Hekimi, Siegfried; Zheng, Huanquan; Champetier, Serge (Winter)
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BIOL 219 Introduction to Physical
Molecular and Cell Biology (4 credits) **
Overview
Biology (Sci) : An introduction to molecular and cell biology from a physical perspective. Techniques and methodologies, both experimental and computational, are included in the presentation of each thematic module.
Terms: Fall 2024
Instructors: Weber, Stephanie; Watt, Alanna; Reyes Lamothe, Rodrigo; Hendricks, Adam (Fall)
Prerequisite(s): BIOL 112; CHEM 110 and CHEM 120; MATH 140, MATH 141 and MATH 133; PHYS 131 and PHYS 142; or the equivalents of these courses.
Corequisite(s): MATH 222 or equivalent
Restriction(s): Not open to students who have taken or are taking ANAT 212, BIOC 212, BIOL 200, and BIOL 201, or BIEN 219. Only open to students in Bioengineering, Computer Science-Biology, Biology-Mathematics, Biology-Quantitative Biology, Chemistry-Biophysical Chemistry, and Physics-Biological Physics Options.
This course is meant to prepare students for related 300-level courses in Biology, Chemistry, Engineering and Physics.
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CHEM 212 Introductory Organic Chemistry 1 (4 credits) ***
Overview
Chemistry : A fundamental study of aliphatic compounds and saturated functional groups including modern concepts of bonding, reaction mechanisms, conformational analysis, spectroscopy, and stereochemistry.
Terms: Fall 2024
Instructors: Vlaho, Danielle; Huot, Mitchell; Sirjoosingh, Pallavi; Tsantrizos, Youla S; Pavelka, Laura; Luedtke, Nathan (Fall)
Fall, Summer
Restriction: Not open to students registered in Chemistry or Biochemistry. Not open to students who have taken or are taking CHEM 211, CHEM 242, or equivalent.
Each lab section is limited enrolment
Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page ().
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PHGY 209 Mammalian Physiology 1 (3 credits)
Overview
Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.
Terms: Fall 2024
Instructors: Vollrath, Melissa; Ragsdale, David S; Shrier, Alvin; Cook, Erik; Aguer, C茅line (Fall)
Fall
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
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PHGY 210 Mammalian Physiology 2 (3 credits)
Overview
Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.
Terms: Winter 2025
Instructors: Vollrath, Melissa; Takano, Tomoko; Lauzon, Anne-Marie; White, John H; Aguer, C茅line (Winter)
Winter
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisite: BIOL 200, BIOL 201, BIOC 212, CHEM 212 or equivalent.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
Although PHGY 210 may be taken without the prior passing of PHGY 209, students should note that they may have some initial difficulties because of lack of familiarity with some basic concepts introduced in PHGY 209
* Students can choose one of ANAT 212, BIOC 212 or BIOL 201.
** Students can choose one of ANAT 212, BIEN 219, BIOC 212, BIOL 200, BIOL 201 or BIOL 219.
*** Cannot be taken by Chemical Engineering students.
Specialization Courses
Minimum of 12 credits from courses below:
Students must select 6 credits from courses outside their department and at least one BMDE course. BMDE courses are best taken near the end of the program, when prerequisites are satisfied.
Physiological Systems, Artificial Cells and Organs
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BIEN 340 Transport Phenomena in Biological Systems 2 (3 credits)
Overview
BIEN : Fundamental principles of mass transport and its application to a variety of biological systems. Membrane permeability and diffusive transport. Convection. Transport across cell membranes. Ion channels. Blood rheology. Active transport. Intra- and inter-cellular transport.
Terms: Winter 2025
Instructors: Kamen, Amine (Winter)
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BIEN 360 Physical Chemistry in Bioengineering (3 credits)
Overview
BIEN : Description of chemical systems with the help of theories of physics and application of its techniques: reaction kinetics, physical and chemical equilibria in biological systems. Review of energy transfer and thermodynamics. Chemical and physical equilibria in biology: variation of Gibbs energy with temperature, energy, composition. Theories of reaction kinetics and the reaction mechanism in biological phenomena: polymerization, protein folding, enzymes.
Terms: Winter 2025
Instructors: Coulombe-Huntington, Jasmin (Winter)
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BIEN 462 Engineering Principles in Physiological Systems (3 credits)
Overview
BIEN : Basic aspects of human physiology. Applications of general balance equations and control theory to systems physiology. The course will cover: circulatory physiology, nervous system physiology, renal physiology and the musculoskeletal system.
Terms: Winter 2025
Instructors: Mitsis, Georgios (Winter)
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BIEN 540 Information Storage and Processing in Biological Systems (3 credits)
Overview
BIEN : Storage and processing of information in biological systems, both natural and artificially-created, ranging from biomolecules, cells, and populations of cells. Information storage in DNA and DNA computation; molecular surfaces of proteins; computation with motile biological agents in networks; and biological and biologically-inspired algorithms.
Terms: Winter 2025
Instructors: Coulombe-Huntington, Jasmin (Winter)
(3-2-4)
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BMDE 505 Cell and Tissue Engineering (3 credits)
Overview
Biomedical Engineering : Application of the principles of engineering, physical, and biological sciences to modify and create cells and tissues for therapeutic applications will be discussed, as well as the industrial perspective and related ethical issues.
Terms: Winter 2025
Instructors: Prakash, Satya (Winter)
(3-0-6)
1.5 hours lecture/1.5 hours seminar per week
Restriction: graduate and final year undergraduate students from physical, biological, and medical science, and engineering.
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PHGY 311 Channels, Synapses and Hormones (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.
Terms: Fall 2024
Instructors: Cooper, Ellis; Sjostrom, Per Jesper; Krishnaswamy, Arjun; Sharif Naeini, Reza (Fall)
Fall
3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term
Prerequisite: PHGY 209 or permission of the instructor.
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PHGY 312 Respiratory, Renal, and Cardiovascular Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.
Terms: Winter 2025
Instructors: Hanrahan, John W; Martin, James G; Shrier, Alvin; Magder, Sheldon A (Winter)
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PHGY 313 Blood, Gastrointestinal, and Immune Systems Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.
Terms: Winter 2025
Instructors: Mandl, Judith; Blank, Volker Manfred; Vollrath, Melissa; Fritz, J枚rg; Quail, Daniela (Winter)
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PHGY 518 Artificial Cells (3 credits)
Overview
Physiology : Physiology, biotechnology, chemistry and biomedical application of artificial cells, blood substitutes, immobilized enzymes, microorganisms and cells, hemoperfusion, artificial kidneys, and drug delivery systems. PHGY 517 and PHGY 518 when taken together, will give a complete picture of this field. However, the student can select one of these.
Terms: Fall 2024
Instructors: Chang, Thomas Ming Swi; Shum-Tim, Dominique; Prakash, Satya; Hoesli, Corinne; Chen, Guojun (Fall)
Fall
Prerequisite (Undergraduate): permission of instructors.
Bioinformatics, Genomics and Proteomics
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ANAT 365 Cellular Trafficking (3 credits)
Overview
Anatomy & Cell Biology : This course explores the fundamental mechanisms that govern the organizations of intracellular membranes, how vesicle generation is signaled, how the membranes curve and bud, and how vesicles know where to go and fuse. In addition to intracellular vesicles, the principles of mitochondrial dynamics and process of cellular autophagy are examined. Also, there is a focus on "Applied Cell Biology", with respect to how the exquisite regulation of cellular transport plays a central role in complex biological systems. A series of modules will take students through the mechanisms of cellular polarity, neurotransmission, metabolic cell biology, pathogen invasion, and more. The emphasis is on the morphological aspects of the processes, and on the major techniques that led to discovery.
Terms: Fall 2024
Instructors: Zeytuni, Natalie; McBride, Heidi; Kennedy, Timothy E; Stroh, Thomas; Presley, John; Sossin, Wayne Steven; Estall, Jennifer (Fall)
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ANAT 458 Membranes and Cellular Signaling (3 credits) *
Overview
Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2025
Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter (Winter)
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BIEN 310 Introduction to Biomolecular Engineering (3 credits)
Overview
BIEN : Forward and reverse engineering of biomolecular systems. Principles of biomolecular thermodynamics and kinetics. Structure and function of the main classes of biomolecules including proteins, nucleic acids, and lipids. Biomolecular systems as mechanical, chemical, and electrical systems. Rational design and evolutionary methods for engineering functional proteins, nucleic acids, and gene circuits. Rational design topics include molecular modeling, positive and negative design paradigms, simulation and optimization of equilibrium and kinetic properties, design of catalysts, sensors, motors, and circuits. Evolutionary design topics include evolutionary mechanisms, fitness landscapes, directed evolution of proteins, metabolic pathways, and gene circuits. Systems biology and synthetic biology.
Terms: Fall 2024
Instructors: Xia, Yu; Coulombe-Huntington, Jasmin (Fall)
Prerequisite(s): BIEN 200 or permission of instructor.
(3-0-6)
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BIEN 410 Computational Methods in Biomolecular Engineering (3 credits)
Overview
BIEN : Introduction to computational biomolecular engineering. Biomolecular simulation: deterministic simulation, stochastic simulation. Biomolecular modeling: energy minimization, coarse-grained methods. Computational biomolecular design: protein design, protein docking, and drug design. Computational systems and synthetic biology: computer simulation of biomolecular circuits.
Terms: Fall 2024
Instructors: Xia, Yu; Coulombe-Huntington, Jasmin (Fall)
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BIEN 420 Biodevices Design for Diagnostics and Screening (3 credits)
Overview
BIEN : Design of analytical devices for high throughput screening (HTS) for genomics, proteomics and other 鈥渙mics鈥� applications; and for diagnostics for medical, veterinary, or environmental applications. Assessment of the specific requirements of each 'client' applications, followed by a review of specific regulations and guidelines. Theoretical and practical guidelines regarding the design of a specific micro- or nano-device, and comparison with the established state of the art in the chosen application.
Terms: Winter 2025
Instructors: Sudalaiyadum Perumal, Ayyappasamy (Winter)
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BIEN 540 Information Storage and Processing in Biological Systems (3 credits)
Overview
BIEN : Storage and processing of information in biological systems, both natural and artificially-created, ranging from biomolecules, cells, and populations of cells. Information storage in DNA and DNA computation; molecular surfaces of proteins; computation with motile biological agents in networks; and biological and biologically-inspired algorithms.
Terms: Winter 2025
Instructors: Coulombe-Huntington, Jasmin (Winter)
(3-2-4)
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BIEN 590 Cell Culture Engineering (3 credits)
Overview
BIEN : Basic principles of cell culture engineering, cell line development and cell culture products途 genomics, proteomics and post-translational modifications途 elements of cell physiology for medium design and bioprocessing途 bioreactor design, scale-up for animal cell culture and single use equipment途 challenges in downstream processing of cell-culture derived products途 process intensification: fed-batch, feeding strategies and continuous manufacturing途 scale-down and process modeling途 Process Analytical technologies and Quality by Design (QbD) concept.
Terms: Fall 2024, Winter 2025
Instructors: Jardon, Mario (Fall) Jardon, Mario; Kamen, Amine (Winter)
(3-0-6)
Prerequisite: Permission of instructor.
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BIOC 311 Metabolic Biochemistry (3 credits)
Overview
Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.
Terms: Fall 2024
Instructors: Denis, Maxime; Giguere, Vincent; Gehring, Kalle; Kazak, Lawrence (Fall)
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BIOC 312 Biochemistry of Macromolecules (3 credits)
Overview
Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).
Terms: Winter 2025
Instructors: Huang, Sidong; Richard, Stephane; Sonenberg, Nahum; Tremblay, Michel; Dostie, Josee; Giguere, Vincent; Vera Ugalde, Maria (Winter)
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BIOC 458 Membranes and Cellular Signaling (3 credits) *
Overview
Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2025
Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter (Winter)
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BMDE 508 Introduction to Micro and Nano-Bioengineering (3 credits)
Overview
Biomedical Engineering : The micro and nanotechnologies that drive and support the miniaturization and parallelization of techniques for life sciences research, including different inventions, designs and engineering approaches that lead to new tools and methods for the life sciences - while transforming them - and help advance our knowledge of life.
Terms: Fall 2024
Instructors: Juncker, David (Fall)
(3-0-6)
Prerequisite: Permission of instructor
This course is intended for graduate and advanced undergraduate students having a biological/medical background or an engineering, physical sciences background. Engineering students enrolled in the Minor in Biomedical Engineering, or Honours in Electrical Engineering and Honours in Mechanical Engineering, should be particularly interested.
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COMP 424 Artificial Intelligence (3 credits)
Overview
Computer Science (Sci) : Introduction to search methods. Knowledge representation using logic and probability. Planning and decision making under uncertainty. Introduction to machine learning.
Terms: Fall 2024
Instructors: Meger, David; Farnadi, Golnoosh (Fall)
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COMP 462 Computational Biology Methods (3 credits)
Overview
Computer Science (Sci) : Application of computer science techniques to problems arising in biology and medicine, techniques for modeling evolution, aligning molecular sequences, predicting structure of a molecule and other problems from computational biology.
Terms: Fall 2024
Instructors: Blanchette, Mathieu (Fall)
* Students select either ANAT 458 or BIOC 458.
Biomaterials, Biosensors and Nanotechnology
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BIEN 330 Tissue Engineering and Regenerative Medicine (3 credits)
Overview
BIEN : The history, scope, challenges, ethical considerations, and potential of tissue engineering. In vitro control of tissue development, differentiation, and growth, including relevant elements of immunology compared to in vivo tissue and organ development. Emphasis on the materials, chemical factors, and mechanical cues used in tissue engineering.
Terms: Winter 2025
Instructors: Kinsella, Matt (Winter)
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BIEN 510 Engineered Nanomaterials for Biomedical Applications (3 credits)
Overview
BIEN : Introduction to the interdisciplinary field of biomedical uses of nanotechnology. Emphasis on emerging nanotechnologies and biomedical applications including nanomaterials, nanoengineering, nanotechnology-based drug delivery systems, nano-based imaging and diagnostic systems, nanotoxicology and immunology, and translating nanomedicine into clinical investigation.
Terms: Fall 2024
Instructors: Kinsella, Matt; Sudalaiyadum Perumal, Ayyappasamy (Fall)
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BIEN 550 Biomolecular Devices (3 credits)
Overview
BIEN : Fundamentals of motor proteins in neuronal transport, force generation e.g. in muscles, cell motility and division. A survey of recent advances in using motor proteins to power nano fabricated devices. Principles of design and operation; hands-on-experience in building a simple device.
Terms: Fall 2024
Instructors: Beaudet, Daniel (Fall)
Prerequisite: Permission of instructor.
(3-1-5)
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BIEN 560 Design of Biosensors (3 credits)
Overview
BIEN : Introduction into the motivation of analytical biosensors as well as its fundamental physicochemical challenges. Techniques used to design, fabricate and operate biosensors. Specific applications.
Terms: Fall 2024
Instructors: Wachsmann Hogiu, Sebastian (Fall)
Prerequisite(s): Permission of instructor.
1. (3-2-4)
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BMDE 504 Biomaterials and Bioperformance (3 credits)
Overview
Biomedical Engineering : Biological and synthetic biomaterials, medical devices, and the issues related to their bioperformance. The physicochemical characteristics of biomaterials in relation to their biocompatibility and sterilization.
Terms: Winter 2025
Instructors: Tabrizian, Maryam (Winter)
(3-0-6)
Restriction: Graduate and final-year undergraduate students from physical, biological and medical science, and engineering
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BMDE 505 Cell and Tissue Engineering (3 credits)
Overview
Biomedical Engineering : Application of the principles of engineering, physical, and biological sciences to modify and create cells and tissues for therapeutic applications will be discussed, as well as the industrial perspective and related ethical issues.
Terms: Winter 2025
Instructors: Prakash, Satya (Winter)
(3-0-6)
1.5 hours lecture/1.5 hours seminar per week
Restriction: graduate and final year undergraduate students from physical, biological, and medical science, and engineering.
-
BMDE 508 Introduction to Micro and Nano-Bioengineering (3 credits)
Overview
Biomedical Engineering : The micro and nanotechnologies that drive and support the miniaturization and parallelization of techniques for life sciences research, including different inventions, designs and engineering approaches that lead to new tools and methods for the life sciences - while transforming them - and help advance our knowledge of life.
Terms: Fall 2024
Instructors: Juncker, David (Fall)
(3-0-6)
Prerequisite: Permission of instructor
This course is intended for graduate and advanced undergraduate students having a biological/medical background or an engineering, physical sciences background. Engineering students enrolled in the Minor in Biomedical Engineering, or Honours in Electrical Engineering and Honours in Mechanical Engineering, should be particularly interested.
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CHEE 380 Materials Science (3 credits)
Overview
Chemical Engineering : Structure/property relationship for metals, ceramics, polymers and composite materials. Atomic and molecular structure, bonds, electronic band structure and semi-conductors. Order in solids: crystal structure, disorders, solid phases. Mechanical properties and fracture, physico-chemical properties, design. Laboratory exercises.
Terms: Fall 2024
Instructors: Girard-Lauriault, Pierre-Luc (Fall)
(3-1-5)
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ECSE 424 Human-Computer Interaction (3 credits)
Overview
Electrical Engineering : The course highlights human-computer interaction strategies from an engineering perspective. Topics include user interfaces, novel paradigms in human-computer interaction, affordances, ecological interface design, ubiquitous computing and computer-supported cooperative work. Attention will be paid to issues of safety, usability, and performance.
Terms: Fall 2024
Instructors: Cooperstock, Jeremy (Fall)
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MECH 553 Design and Manufacture of Microdevices (3 credits)
Overview
Mechanical Engineering : Introduction to microelectromechanical systems (MEMS). Micromachining techniques (thin-film deposition; lithography; etching; bonding). Microscale mechanical behaviour (deformation and fracture; residual stresses; adhesion; experimental techniques). Materials- and process-selection. Process integration. Design of microdevice components to meet specified performance and reliability targets using realistic manufacturing processes.
Terms: This course is not scheduled for the 2024-2025 academic year.
Instructors: There are no professors associated with this course for the 2024-2025 academic year.
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MIME 360 Phase Transformations: Solids (3 credits)
Overview
Mining & Materials Engineering : Free energy (equilibrium) and kinetic (non-equilibrium) considerations, phase diagrams and TTT diagrams, solid state diffusion, diffusional (nucleation and growth) and shear (martensitic) transformations.
Terms: Fall 2024
Instructors: Yue, Stephen; Paray, Florence (Fall)
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MIME 362 Mechanical Properties (3 credits)
Overview
Mining & Materials Engineering : Stress-strain behaviour. Elasticity and plasticity of metals, ceramics and polymers. Dislocations theory. Single crystal and polycrystalline slip. Mechanical twinning. Strengthening mechanisms. Process-property and microstructure-property relationships. Notch toughness and fracture mechanics. Failure, fracture and damage accumulation. Fatigue. Creep and creep rupture. Fractography. Design considerations in materials selection.
Terms: Fall 2024
Instructors: Paray, Florence; Amegadzie, Mark; Song, Jun (Fall)
(2-3-4)
Prerequisite: MIME 360
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MIME 470 Engineering Biomaterials (3 credits)
Overview
Mining & Materials Engineering : Key definitions, clinical need, desired materials properties, current and future materials, materials assessments and performance. Materials of the body. Characterisation techniques for bulk and mechanical properties of biomaterials. Engineering processing and design of biomaterials.
Terms: Fall 2024
Instructors: Nazhat, Showan (Fall)
(3-0-6)
Prerequisite: MIME 261 or equivalent. Permission of instructor.
Attendance is mandatory for a one-time 3-hour lab, scheduled during the semester.
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PHYS 534 Nanoscience and Nanotechnology (3 credits)
Overview
Physics : Topics include scanning probe microscopy, chemical self-assembly, computer modelling, and microfabrication/micromachining.
Terms: Fall 2024
Instructors: Grutter, Peter H (Fall)
Fall
Restriction: U3 or graduate students in Physics, Chemistry, or Engineering, or permission of the instructor.
Biomechanics and Prosthetics
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BIEN 320 Molecular, Cellular and Tissue Biomechanics (3 credits)
Overview
BIEN : Basic mechanics of biological building blocks, focusing on the cytoskeleton, with examples from pathology. At the macromolecular level: weak/variable crosslinking and hydrolysis driven athermal processes. At the cellular/tissue level: cell architecture and function. Discussion of modern analytical techniques capable of single-molecule to tissue scale measurements.
Terms: Winter 2025
Instructors: Ehrlicher, Allen (Winter)
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BIEN 570 Active Mechanics in Biology (3 credits)
Overview
BIEN : Introduction to the role of active forces, e.g. cell and tissue contraction, in the mechanics of biological systems. Review of passive and actively driven viscoelastic systems and momentum transport underlying the material properties of biology. The course involves a literature survey and a team project application.
Terms: Fall 2024
Instructors: Ehrlicher, Allen (Fall)
Prerequisite(s): Permission of instructor.
1. (3-2-4)
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BMDE 512 Finite-Element Modelling in Biomedical Engineering (3 credits)
Overview
Biomedical Engineering : General principles of quantitative modelling; types of models; principles of the finite-element method, primarily as applied to mechanical systems; introduction to the use of finite-element software; model generation from imaging data; modelling various material types, mainly biological; model validation.
Terms: Fall 2024
Instructors: Funnell, Robert (Fall)
(3-0-6)
Prerequisite: Differential equations (MATH 271 or equivalent) or permission of instructor
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CHEE 563 Biofluids and Cardiovascular Mechanics (3 credits) *
Overview
Chemical Engineering : Basic principles of circulation including vascular fluid and solid mechanics, modelling techniques, clinical and experimental methods and the design of cardiovascular devices.
Terms: This course is not scheduled for the 2024-2025 academic year.
Instructors: There are no professors associated with this course for the 2024-2025 academic year.
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MECH 315 Mechanics 3 (4 credits)
Overview
Mechanical Engineering : Single-degree-of-freedom systems; free vibrations; effect of damping; response to harmonic, periodic and arbitrary excitation. Lagrange's equations of motion. Vibrations of multi-degree-of-freedom systems. Continuous systems.
Terms: Fall 2024, Winter 2025
Instructors: Mongeau, Luc (Fall) Mongeau, Luc (Winter)
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MECH 321 Mechanics of Deformable Solids (3 credits)
Overview
Mechanical Engineering : Modern phenomenological theories of the behaviour of engineering materials. Stress and strain concepts and introduction to constitutive theory. Applications of theory of elasticity and thermoelasticity. Introduction to finite element stress analysis method and its application to structural design of a machine element.
Terms: Fall 2024, Winter 2025
Instructors: Hubert, Pascal (Fall) Li, Jianyu (Winter)
(3-1-5)
Prerequisite: CIVE 207
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MECH 530 Mechanics of Composite Materials (3 credits)
Overview
Mechanical Engineering : Fiber-reinforced composites. Stress, strain, and strength of composite laminates and honeycomb structures. Failure modes and failure criteria. Environmental effects. Manufacturing processes. Design of composite structures. Computer modelling of composites. Computer techniques are utilized throughout the course.
Terms: Fall 2024
Instructors: Lessard, Larry (Fall)
(3-0-6)
Corequisite: MECH 321 or equivalent/instructor's permission.
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MECH 561 Biomechanics of Musculoskeletal Systems (3 credits)
Overview
Mechanical Engineering : The musculoskeletal system; general characteristics and classification of tissues and joints. Biomechanics and clinical problems in orthopaedics. Modelling and force analysis of musculoskeletal systems. Passive and active kinematics. Load-deformation properties of passive connective tissue, passive and stimulated muscle response. Experimental approaches, case studies.
Terms: Fall 2024
Instructors: Dukkipati, Siril Teja (Fall)
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MECH 563 Biofluids and Cardiovascular Mechanics (3 credits) *
Overview
Mechanical Engineering : Basic principles of circulation including vascular fluid and solid mechanics, modelling techniques, clinical and experimental methods and the design of cardiovascular devices.
Terms: Winter 2025
Instructors: There are no professors associated with this course for the 2024-2025 academic year.
-
MIME 360 Phase Transformations: Solids (3 credits)
Overview
Mining & Materials Engineering : Free energy (equilibrium) and kinetic (non-equilibrium) considerations, phase diagrams and TTT diagrams, solid state diffusion, diffusional (nucleation and growth) and shear (martensitic) transformations.
Terms: Fall 2024
Instructors: Yue, Stephen; Paray, Florence (Fall)
-
MIME 362 Mechanical Properties (3 credits)
Overview
Mining & Materials Engineering : Stress-strain behaviour. Elasticity and plasticity of metals, ceramics and polymers. Dislocations theory. Single crystal and polycrystalline slip. Mechanical twinning. Strengthening mechanisms. Process-property and microstructure-property relationships. Notch toughness and fracture mechanics. Failure, fracture and damage accumulation. Fatigue. Creep and creep rupture. Fractography. Design considerations in materials selection.
Terms: Fall 2024
Instructors: Paray, Florence; Amegadzie, Mark; Song, Jun (Fall)
(2-3-4)
Prerequisite: MIME 360
* Students choose either CHEE 563 or MECH 563.
Medical Physics and Imaging
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BIEN 350 Biosignals, Systems and Control (4 credits) *
Overview
BIEN : Discrete- and continuous-time signals; basic system properties. Linear time-invariant systems; convolution. Frequency domain analysis; filtering; sampling. Laplace and Fourier transforms; transfer functions; poles and zeros; transient and steady state response. Z-transforms. Dynamic behaviour and PID control of first- and second-order processes. Stability. Applications to biological systems, such as central nervous, cognitive, and motor systems.
Terms: Fall 2024
Instructors: Mitsis, Georgios (Fall)
(3-3-6)
Prerequisite(s): MATH 263 or permission of instructor.
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BIEN 530 Imaging and Bioanalytical Instrumentation (3 credits)
Overview
BIEN : Microscopy techniques with application to biology and medicine. Practical introduction to optics and microscopy from the standpoint of biomedical research. Discussion of recent literature; hands-on experience. Topics include: optics, contrast techniques, advanced microscopy, and image analysis.
Terms: Winter 2025
Instructors: Hendricks, Adam (Winter)
Prerequisite: Permission of instructor.
(3-1-5)
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BMDE 512 Finite-Element Modelling in Biomedical Engineering (3 credits)
Overview
Biomedical Engineering : General principles of quantitative modelling; types of models; principles of the finite-element method, primarily as applied to mechanical systems; introduction to the use of finite-element software; model generation from imaging data; modelling various material types, mainly biological; model validation.
Terms: Fall 2024
Instructors: Funnell, Robert (Fall)
(3-0-6)
Prerequisite: Differential equations (MATH 271 or equivalent) or permission of instructor
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BMDE 519 Biomedical Signals and Systems (3 credits)
Overview
Biomedical Engineering : An introduction to the theoretical framework, experimental techniques and analysis procedures available for the quantitative analysis of physiological systems and signals. Lectures plus laboratory work using the Biomedical Engineering computer system. Topics include: amplitude and frequency structure of signals, filtering, sampling, correlation functions, time and frequency-domain descriptions of systems.
Terms: Fall 2024
Instructors: Kearney, Robert E (Fall)
(3-0-6)
Prerequisites: Satisfactory standing in U3 Honours Physiology; or U3 Major in Physics-Physiology; or U3 Major Physiology-Mathematics; or permission of instructor
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COMP 424 Artificial Intelligence (3 credits)
Overview
Computer Science (Sci) : Introduction to search methods. Knowledge representation using logic and probability. Planning and decision making under uncertainty. Introduction to machine learning.
Terms: Fall 2024
Instructors: Meger, David; Farnadi, Golnoosh (Fall)
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COMP 558 Fundamentals of Computer Vision (4 credits)
Overview
Computer Science (Sci) : Image filtering, edge detection, image features and histograms, image segmentation, image motion and tracking, projective geometry, camera calibration, homographies, epipolar geometry and stereo, point clouds and 3D registration. Applications in computer graphics and robotics.
Terms: Fall 2024
Instructors: Siddiqi, Kaleem (Fall)
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ECSE 206 Introduction to Signals and Systems (3 credits) *
Overview
Electrical Engineering : Review of complex functions. Discrete-and continuous-time signals, basic system properties. Linear time-invariant systems, convolution. Fourier series and Fourier transforms, frequency-domain analysis, filtering, sampling. Laplace transforms and inversion, transfer functions, poles and zeros, solutions of linear constant-coefficient differential equations, transient and steady-state response. Z-transforms.
Terms: Fall 2024, Winter 2025
Instructors: Chen, Lawrence (Fall) Armanfard, Narges (Winter)
Prerequisite(s): ECSE 200
(3-2-4)
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ECSE 412 Discrete Time Signal Processing (3 credits)
Overview
Electrical Engineering : Discrete-time signals and systems; Fourier and Z-transform analysis techniques, the discrete Fourier transform; elements of FIR and IIR filter design, filter structures; FFT techniques for high speed convolution; quantization effects.
Terms: Fall 2024
Instructors: Champagne, Benoit (Fall)
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PHYS 557 Nuclear Physics (3 credits)
Overview
Physics : General nuclear properties, nucleon-nucleon interaction and scattering theory, radioactivity, nuclear models, nuclear reactions.
Terms: Fall 2024
Instructors: Gale, Charles (Fall)
Fall
3 hours lectures
Restriction: U3 Honours students, graduate students, or permission of the instructor
* Students choose either BIEN 350 or ECSE 206.
Neural Systems and Biosignal Processing
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BIEN 350 Biosignals, Systems and Control (4 credits) *
Overview
BIEN : Discrete- and continuous-time signals; basic system properties. Linear time-invariant systems; convolution. Frequency domain analysis; filtering; sampling. Laplace and Fourier transforms; transfer functions; poles and zeros; transient and steady state response. Z-transforms. Dynamic behaviour and PID control of first- and second-order processes. Stability. Applications to biological systems, such as central nervous, cognitive, and motor systems.
Terms: Fall 2024
Instructors: Mitsis, Georgios (Fall)
(3-3-6)
Prerequisite(s): MATH 263 or permission of instructor.
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BIEN 462 Engineering Principles in Physiological Systems (3 credits)
Overview
BIEN : Basic aspects of human physiology. Applications of general balance equations and control theory to systems physiology. The course will cover: circulatory physiology, nervous system physiology, renal physiology and the musculoskeletal system.
Terms: Winter 2025
Instructors: Mitsis, Georgios (Winter)
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BMDE 501 Selected Topics in Biomedical Engineering (3 credits)
Overview
Biomedical Engineering : An overview of how techniques from engineering and the physical sciences are applied to the study of selected physiological systems and biological signals. Using specific biological examples, systems will be studied using: signal or finite-element analysis, system and identification, modelling and simulation, computer control of experiments and data acquisition.
Terms: Fall 2024
Instructors: Bzdok, Danilo (Fall)
(3-0-6)
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BMDE 502 BME Modelling and Identification (3 credits)
Overview
Biomedical Engineering : Methodologies in systems or distributed multidimensional processes. System themes include parametric vs. non-parametric system representations; linear/non-linear; noise, transients and time variation; mapping from continuous to discrete models; and relevant identification approaches in continuous and discrete time formulations.
Terms: This course is not scheduled for the 2024-2025 academic year.
Instructors: There are no professors associated with this course for the 2024-2025 academic year.
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BMDE 503 Biomedical Instrumentation (3 credits)
Overview
Biomedical Engineering : The principles and practice of making biological measurements in the laboratory, including theory of linear systems, data sampling, computer interfaces and electronic circuit design.
Terms: Fall 2024
Instructors: Wagner, Ross (Fall)
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BMDE 519 Biomedical Signals and Systems (3 credits)
Overview
Biomedical Engineering : An introduction to the theoretical framework, experimental techniques and analysis procedures available for the quantitative analysis of physiological systems and signals. Lectures plus laboratory work using the Biomedical Engineering computer system. Topics include: amplitude and frequency structure of signals, filtering, sampling, correlation functions, time and frequency-domain descriptions of systems.
Terms: Fall 2024
Instructors: Kearney, Robert E (Fall)
(3-0-6)
Prerequisites: Satisfactory standing in U3 Honours Physiology; or U3 Major in Physics-Physiology; or U3 Major Physiology-Mathematics; or permission of instructor
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ECSE 206 Introduction to Signals and Systems (3 credits) *
Overview
Electrical Engineering : Review of complex functions. Discrete-and continuous-time signals, basic system properties. Linear time-invariant systems, convolution. Fourier series and Fourier transforms, frequency-domain analysis, filtering, sampling. Laplace transforms and inversion, transfer functions, poles and zeros, solutions of linear constant-coefficient differential equations, transient and steady-state response. Z-transforms.
Terms: Fall 2024, Winter 2025
Instructors: Chen, Lawrence (Fall) Armanfard, Narges (Winter)
Prerequisite(s): ECSE 200
(3-2-4)
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ECSE 517 Neural Prosthetic Systems (3 credits)
Overview
Electrical Engineering : Selected topics in bioengineering focusing on the principles of neural prosthetics systems (brain machine interfaces). Paralysis as a communication problem. Motor control theory receptive fields. Electrical properties of the central nervous system, modern measurement technologies, encoding and mutual information, statistical data analysis, decoding and thought prediction.
Terms: This course is not scheduled for the 2024-2025 academic year.
Instructors: There are no professors associated with this course for the 2024-2025 academic year.
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ECSE 526 Artificial Intelligence (3 credits)
Overview
Electrical Engineering : Design principles of autonomous agents, agent architectures, machine learning, neural networks, genetic algorithms, and multi-agent collaboration. The course includes a term project that consists of designing and implementing software agents that collaborate and compete in a simulated environment.
Terms: Fall 2024
Instructors: Cooperstock, Jeremy (Fall)
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PHYS 413 Physical Basis of Physiology (3 credits)
Overview
Physics : Analytic and computer simulation techniques are used to examine the role of nonlinearities and time delays in determining the dynamic behaviour of physiological control systems and their relation to normal and pathophysiological states. Examples drawn from the control of respiration, cellular proliferation and differentiation, biochemical feedback networks, thermoregulatory mechanisms, and neural feedback.
Terms: This course is not scheduled for the 2024-2025 academic year.
Instructors: There are no professors associated with this course for the 2024-2025 academic year.
* Students choose either BIEN 350 or ECSE 206.
0-6 credits can be taken by permission of the Departmental Adviser and approval of the Minor Adviser.
